“…As usual in our Laboratory of Experimental Hypnosis at the University of Padua (Casiglia et al, 1997(Casiglia et al, , 2006(Casiglia et al, , 2007(Casiglia et al, , 2010(Casiglia et al, , 2012a(Casiglia et al, , 2012b(Casiglia et al, , 2015(Casiglia et al, , 2016Facco, Casiglia, Masiero, Tikhonoff, Giacomello & Zanette, 2011;Giordano, Tikhonoff, Tosello, Lapenta, & Casiglia, 2012;Tikhonoff et al, 2012;Tikhonoff, Senzolo, Lapenta, Palatini, & Casiglia, 2017), in designing the protocol, specific attention was paid to using standardized instruments commonly employed in physiology and cardiology in order to make the study repeatable. As previously demonstrated both by our Laboratory (Casiglia et al, 2007(Casiglia et al, , 2015(Casiglia et al, , 2016Facco et al, 2011) and by other research groups (Sharav & Tal, 2004;Chaves & Dworkin, 1997), hypnotic focused analgesia (HFA) prevents pain in a real, measurable and repeatable way, also reducing or even abolishing the reflex autonomic response to pain. We induced ischemic pain by immersing the participant's hand in icy water at 0˚C temperature (a procedure called cold pressor test, CPT, used by cardiologists in the study of the coronary reserve) (Mitchell, MacDonald, & Brodie, 2004;Peckerman et al, 1998;Sevre & Rostrup, 1999).…”