2021
DOI: 10.21203/rs.3.rs-696316/v1
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Effects of hypercholesterolism on expansion of abdominal aortic aneurysm in rat model

Abstract: Background Inflammation is recognized as a critical process in expansion of abdominal aortic aneurysm (AAA). A relationship between effects of cholesterol and statin in this process have been suggested, but remain untested. Therefore, current study aimed to examine the effects of hypercholesterolism on expansion of AAA in a rat model. Methods A total of 16 male rats were divided into 4 groups as follows: group I, normocholesterol diet and saline infusion, group II, normocholesterol diet and porcine pancreati… Show more

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