Effects of hyperbaric oxygen therapy on fibrovascular ingrowth in porous polyethylene blocks implanted under burn scar tissue: An experimental study

Dinar, Serkan; Ağır, Hakan; Chen, Sen; Yazır, Yusufhan; Dalçik, Hakkı; Unal, Cigdem

doi:10.1016/j.burns.2007.04.014

Cited by 21 publications

(9 citation statements)

References 28 publications

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“…2,11 In addition, HBOT has been shown to increase fibroblast proliferation and collagen production in healing wounds. 12 Treatment protocols for HBOT are variable. HBOT is usually administered at 2 to 3 atm once or twice daily for 20 to 40 days.…”

Section: Discussionmentioning

confidence: 99%

Hyperbaric oxygen therapy for the treatment of anastomotic complications after tracheal resection and reconstruction

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Gukasyan

Muniappan

et al. 2014

The Journal of Thoracic and Cardiovascular Surgery

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Section: Discussionmentioning

confidence: 99%

Hyperbaric oxygen therapy for the treatment of anastomotic complications after tracheal resection and reconstruction

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Gukasyan

Muniappan

et al. 2014

The Journal of Thoracic and Cardiovascular Surgery

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“…(92) Enhanced collagen synthesis and cross-linking by HBO 2 have been described, but whether changes are linked to the O 2 -dependence of fibroblast hydroxylases, alteration in balance of wound growth factors, metalloproteinases and/or inhibitors of metalloproteases, is as yet unclear. (92, 93)…”

Section: Wound Healingmentioning

confidence: 99%

Hyperbaric Oxygen: Its Mechanisms and Efficacy

Thom¹

2011

Plastic and Reconstructive Surgery

480

401

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“…Oxidative stress at sites of neovascularization stimulates growth factor synthesis by augmenting synthesis and stabilization of hypoxia‐inducible factor 1, a process further enhanced by HBO . HBO also enhances extracellular matrix formation, an O 2 ‐dependent process closely linked to neovascularization .…”

Section: Introductionmentioning

confidence: 99%

Hyperbaric oxygen therapy as treatment of diabetic foot ulcers

Löndahl

2012

Diabetes Metabolism Res

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SummaryHyperbaric oxygen therapy (HBO) could be described as a short-term, highdose oxygen inhalation and diffusion therapy, delivered systemically through airways and blood, achieved by having the patient breathing concentrated oxygen at a pressure higher than 1 absolute atmosphere. In clinical practice, monoplace or multiplace hyperbaric chambers are used to achieve this. Treatment is usually given as daily 90-to 120-min-long HBO sessions at pressures between 2.0 and 2.5 absolute atmosphere, aiming for 30-40 treatment sessions. The use of HBO as treatment of diabetic foot ulcers has been founded on weak scientific ground, although the outcomes from previous studies are in concert with the conclusions from preclinical studies and supports the theoretical framework of HBO reversing hypoxia-induced pathology. Two well-designed randomized double-blind trials have put HBO on firmer ground and may justify adjunctive HBO treatment to a selected group of patients with nonhealing diabetic foot ulcers. Some health economic studies suggest potential cost effectiveness, but these studies are limited by deficient primary clinical data and should be interpreted with caution. Several issues remain to be addressed, such as developing robust criteria to improve treatment protocols, determining which patients are likely to benefit, and when to start and stop treatment.

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Effects of hyperbaric oxygen therapy on fibrovascular ingrowth in porous polyethylene blocks implanted under burn scar tissue: An experimental study

Cited by 21 publications

References 28 publications

Hyperbaric oxygen therapy for the treatment of anastomotic complications after tracheal resection and reconstruction

Hyperbaric oxygen therapy for the treatment of anastomotic complications after tracheal resection and reconstruction

Hyperbaric Oxygen: Its Mechanisms and Efficacy

Hyperbaric oxygen therapy as treatment of diabetic foot ulcers

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