Effects of hyperbaric oxygen therapy on periodontal disease: a literature review

Abstract

Background and objective: Hyperbaric oxygen (HBO2) has been the subject of research in many areas of dentistry. HBO2 seems to be a useable, additional treatment method. However, there are still no certain conclusions and clear guidelines for procedures. The aim of the study was to collect current literature assessing the use of hyperbaric oxygen therapy in the treatment of periodontitis. Materials and Methods: The following review was performed using medical databases Medline via PubMed and Google Scholar. The review presents articles which assess the effect of hyperbaric oxygen therapy in combination with non-surgical scaling and root planing (SRP) in patients with periodontitis as an adjunctive method to standard protocols. Results: There are potentially plausible mechanisms by which HBO2 could be beneficial. Further welldesigned science research and clinical trials are needed. Due to a small body of literature, differences in methodology and observation periods the data are not sufficient for statistical analysis. Conclusion: The use of HBO2 seems to be reasonable as an adjunct method of the periodontitis treatment. However, authors of this literature review could not unambiguously state that hyperbaric oxygen therapy could be commonly recommended as a potential method of periodontitis treatment. It is essential to develop consistent protocols for the procedure and further research in this area. DOI: 10.22462/01.01.2023.17

Pilot Study: The Effectiveness of Hyperbaric Oxygen Therapy in the Treatment of Periodontitis in Patients with Type 2 Diabetes

“…Only a statistically greater reduction was obtained for (p < 0.05) BOP in the study group compared to the control group. The authors concluded that HBO therapy in combination with subgingival mechanotherapy can be an effective treatment for moderate to severe forms of periodontitis [26]. A study by Mulawarmanti et al (2019) in animals with diabetes and periodontitis showed a statistically significant reduction in IL-1β expression and an increase in IL-10 expression after treatment with HBO and HBO in combination with 3% Stichopus hermanii gel [27].…”