Abstract:Context Although vitrification is commonly used for oocyte cryopreservation, the cryogenic damage results in poor developmental capacity of oocytes after freezing. Nano-cryopreservation is one of the new methods of vitrification developed in recent years. However, the effect of nano-cryopreservation on mature bovine oocytes remains to be elucidated. Aims This study aimed to verify the effect of using hydroxyapatite (HA) nanoparticles (NPs) on the vitrification of bovine metaphase II (MII)-stage oocytes… Show more
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