Effects of hydrolyzed <i>Chlorella vulgaris</i>
 by malted barley on the immunomodulatory response in ICR mice and in Molt-4 cells

Kim, Na-Hyung; Kim, Kyu-Yeob; Jeong, Hyun‐Ja; Kim, Hyung-Min; Hong, Seung‐Heon; Um, Jae‐Young

doi:10.1002/jsfa.3989

Cited by 10 publications

(11 citation statements)

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“…Reduction of the immobility time during forced swimming test traditionally interpreted as a measure of 'behavioral despair' or 'learned helplessness' (Gao et al, 2014). Many studies show the possibility that retrenchment the amount of time an animal spends immobile in the forced swimming test by natural compounds have the relation with cytokines and blood parameters (Shin et al, 2004;Kim et al, 2008;Kim et al, 2010) However, it was not illuminated yet detail mechanism on its relation between immobility time and change of cytokines/ blood parameters. The immobility time of mice in fluoxetine administrated groups, LF administrated groups, and betaine administrated groups reduced significantly at the last day, compared with saline administrated group (P < 0.05).…”

Section: Resultsmentioning

confidence: 99%

“…Thus, the reduction of BUN values by LF and betaine indicated that they could have a play in alleviating kidney injury by forced swimming test. Immunoregulatory cytokines play an important role in immune response (Bernabei et al, 2003;Kim et al, 2010). Of these immunoregulartory cytokines, they are known that IFN- produced by T and natural killer cells is considered the principal effector cytokine of cell-mediated immunity, and IL-2 is a T cell growth factor, can augment natural killer cell cytolytic activity, or promotes immunoglobulin production by B cells (Kim et al, 2006;Lenardo, 1991).…”

Section: Resultsmentioning

confidence: 99%

“…The feeling of fatigue is also recognized in chronic medical illness including an inmate of a hospital in intensive care unit or enteral/parenteral feeding condition (Kim et al, 2008). Forced swimming test causes alterations in cellular and non-cellular immunity, lowers the ratio of lymphocytes, enhances the ratio of neutrophils in rat peripheral blood (Dubovik and Bogomazov, 1987;Delbende et al, 1994;Connor et al, 1997;Kim et al, 2010). In addition, Shin et al (2004) have demonstrated on a relationship between immune function and immobility time after a forced swimming test by ICR mice.…”

Section: Research Articlementioning

confidence: 99%

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Effects of Lycium chinense Miller Fruit and its Constituent Betaine on Immunomodulation in Balb/c Mice

Kim

Baek

2014

Korean Journal of Environmental Agriculture

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BACKGROUND:The aim of this study is to investigate the effects of Lycium chinense Miller fruit and its representative constituent betaine on reduction of immobility time and blood parameters in balb/c mice. METHODS AND RESULTS:We investigated the immobility time and the changes in aspects of blood biochemical parameters by the administration of L. chinense Miller fruit and its representative constituent betaine, after the forced swimming test. The immobility time was significantly reduced about 41.3% and 53.6%, respectively, in the animal of L. chinense Miller fruit and its representative constituent betaine-administrated group for 7 days, in comparison with that of the control group. The level of blood urea nitrogen was significantly decreased in L. chinense Miller fruit and its representative constituent betaine-treated group compared with the control group (P < 0.05), respectively. In addition, the interlukin-2 levels of mice in L. chinense Miller fruit and betaine treated group was increased compared with the control group. CONCLUSION: These results indicate that L. chinense Miller fruit and betaine might be helpful in the immune

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Research Articlementioning

confidence: 99%

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Effects of Lycium chinense Miller Fruit and its Constituent Betaine on Immunomodulation in Balb/c Mice

Kim

Baek

2014

Korean Journal of Environmental Agriculture

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“…Apart from its effect on water quality, the abundance of Chlorella in green water ponds might have helped to improve the shrimp's immune competence to resist disease thus resulting in higher survival (Ponprateep et al, 2011;Tendencia et al, 2012). It has been reported that hydrolysed Chlorella vulgaris promotes the release of interferons (IFN) in mice (Kim et al, 2010). Furthermore, IFNs have protective immuno-modulatory function against pneumonia virus in mice leading to high survival (Rigaux et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Green water technology for the production of pacific white shrimp, Penaeus vannamei (Boone, 1931)

Chithambaran

Harbi²,

Broom³

et al. 2017

Indian J. Fish.

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Materials and methods Design of experimentThe experiment was conducted in 6 high density polyethylene (HDPE) lined ponds (300 m 2 ) at King Abdulaziz University (KAU) Fish Farm, Faculty of Marine Sciences, Obhur, Jeddah for a period of 96 days. Semi-intensive type of culture method was followed for rearing shrimp. Both control and treatment experimental ponds were triplicated. All ponds were sundried and limed ABSTRACT A study was conducted to assess the efficiency of green water culture strategy for production of Pacific white shrimp Penaeus vannamei (Boone, 1931) in high density polyethylene (HDPE) lined ponds (300 m 2 ) for a period of 96 days. Green water from a broodstock fish pond was used for rearing shrimp in treatment ponds; whereas, filtered seawater was used for growing shrimp in control ponds, with both treatment and control in triplicates. Shrimp juveniles (specific pathogen free, SPF) of uniform size (1.74±0.46 g) were stocked at the rate of 100 nos. m -2 per pond. Feeding, water exchange, sampling and water quality analysis were done as per standard shrimp growout procedure. Shrimp health status and microbial load in culture ponds were recorded periodically. Water quality parameters did not show significant variations between control and treatment ponds. Enhanced growth, survival (19.7%) and biomass (23.3%) were observed in treatment ponds when compared to control. Significant reduction in bacterial population and improved shrimp health status were also noticed in treatment ponds. Green water culture technique reduced harmful bacterial population in culture ponds and enhanced shrimp growth, survival, health and production.

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“…클로렐라 내 함유되어 있는 CGF(chlorella growth factor)는 성장 촉진 물질로서, 항암효과 (Justo, 2001;Noda et al, 1996), 성인병 예방 효과 (Hasegawa et al, 1995) 및 골다공증의 예방에 효 과적인 것으로 보고된 바 있다 (Jung, 2003;Kim et al, 2003). Kim et al(2010) - Table 2에서 나타내었다. 실험 종료에 따른 육계 체중을 조사한 결과, 클로렐라 사 료첨가제 0.5%(T4) 및 1.0% 급여구(T3)에서 각각 1,670 g, 1,672 g 으로 대조구 및 다른 처리구와 비교 시 유의적으로 높게 나타났으며(P<0.05), 증체량 역시 클로렐라 사료첨가 제 급여 처리구(T3 및 T4)에서 유의적인 개선 효과를 나타 내었었다(P<0.05). 사료 섭취량 및 사료 요구율은 처리구간 Table 4.…”

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Effect of Dietary Chlorella Supplementation on Growth Performance, Immune Response, and Intestinal Micro Flora Concentration of Broiler Chickens

Kang¹,

Choi²,

Kim³

et al. 2013

Korean Journal of Poultry Science

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A study was conducted to investigate the effect of dietary supplementation of feedstuff of Chlorella (Chlorella vulgaris) to replace of antibiotic in the diets of broiler chickens. A total of 720 1-d-old straight run broiler chicks (Ross × Ross) was randomly assigned into six treatments with four replicate pens (30 birds/replicate pen) for 5-wk. A corn-soy bean meal basal diet was formulated, the treatment groups were negative group (NC, antibiotic-free diet) and 0.1% virginiamycin in as antibiotic growth promoters (PC), 1.0% fresh liquid Chlorella (T1), 1.0% dried Chlorella powder (T2), 1.0% commercial Chlorella product and 1.0% (T3) and commercial Chlorella product 0.5% (T4) were added to the basal diet to form six dietary treatments. No significant differences were found among the treatments for feed intake and feed conversion of broiler chickens during the whole experimental period, but the BW gain was significantly higher (P<0.05) in commercial Chlorella product supplemental groups than the control group (NC and PC groups). Dietary supplementation of Chlorella significantly (P<0.05) increased the plasma IgA, IgM and IgG concentration of chicks compared to NC and PC groups. Supplemental AGPs and commercial chlorella product did not affect the E. coli and Salmonella concentration in the intestinal microflora of broiler chicks; however, the population of Lactobacillus was significantly increased (P<0.05) when birds were fed commercial Chlorella product groups. It is concluded that commercial Chlorella product supplementation could be used as an alternative of antibiotics to promote growth and immune response by increasing the production of lactic acid bacteria in the intestinal microflora of broiler chickens.

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Effects of hydrolyzed Chlorella vulgaris by malted barley on the immunomodulatory response in ICR mice and in Molt-4 cells

Abstract: These results indicate that hydrolyzed Chlorella vulgaris by malted barley is useful for immune function improvements, enhanced physical stamina, and as a candidate for an anti-fatigue or antidepressant agent.

Cited by 10 publications

References 40 publications

Effects of Lycium chinense Miller Fruit and its Constituent Betaine on Immunomodulation in Balb/c Mice

Effects of Lycium chinense Miller Fruit and its Constituent Betaine on Immunomodulation in Balb/c Mice

Green water technology for the production of pacific white shrimp, Penaeus vannamei (Boone, 1931)

Effect of Dietary Chlorella Supplementation on Growth Performance, Immune Response, and Intestinal Micro Flora Concentration of Broiler Chickens

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