Effects of human amniotic fluid on cartilage regeneration from free perichondrial grafts in rabbits

Amniyotik membran ve sıvı kaynaklı tedaviler – kök hücre tedavisi

“…[12] AS epidermal büyüme faktörü, IGF-I, IGF-II, FGF, fibronektin, laminin hiyaluronik asit, kondroitin sülfat ve hiyaluronik asit aktive edici faktör gibi bazı kemik ve kıkırdak tamir mekanizmalarında yerleri olan ekstrasellüler makromoleküller yönünden de zengindir. [38] Özgenel ve arkadaşları, fare kulak perikondriumunda AS'nin kondrogenezi arttırdığını tespit etmişlerdir. Kavaklı ve arkadaşları, tavşan kostal kıkır-dağında insan AS'sinin kondrogenezi arttırdığını tespit etmişlerdir.…”

Líquido amniótico tópico: uma potencial nova alternativa para doenças da superfície ocular

“…Têm sido realizados estudos em coelhos sob o efeito do LAH em cartilagens (28)(29) . Os autores demonstraram que o LAH foi capaz de aumentar a formação de cartilagem a partir de enxerto pericondrial livre.…”

The effect of human amniotic fluid on mandibular distraction osteogenesis

“…12,16 HAF, generally obtained by amniocentesis during the second trimester of gestation, contains high molecular weight HA and HASA in high concentrations. [14][15][16][17] HA has been shown to increase osteoblastic bone formation in vitro, through increased mesenchymal cell differentiation and migration. 15,17 Also, HASA has been shown to stimulate and increase the production of endogenous HA.…”

“…12 A rich content of growth and trophic factors such as epidermal growth factor (EGF), FGF, and insulin-like growth factors I and II (IGF-I and IGF-II), which are critical for development, have been identified in human amniotic fluid (HAF). [12][13][14][15] Additionally, hyaluronic acid (HA), hyaluronic acid stimulating activator (HASA), chondroitin-4-and -6-sulphate, dermatan sulphate, and heparan sulphate have been identified in HAF. 12,16 HAF, generally obtained by amniocentesis during the second trimester of gestation, contains high molecular weight HA and HASA in high concentrations.…”