Effects of hollow fiber packing fraction on blood flow pattern and gas transfer rate of an intravascular oxygenator (IVOX)

Newly Developed Pediatric Membrane Oxygenator that Suppresses Excessive Pressure Drop in Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation (ECMO)

“…Since the pressure drop with respect to the blood flow rate increases quadratically, the blood flow is turbulent flow and contributes to the increase in gas transfer rate [12][13][14][15][16]. Figure 14 (a) shows the relationship between the blood flow rate and oxygen transfer rate of both pediatric membrane oxygenators.…”

“…Numerous studies have been conducted on the design of membrane oxygenators [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. Matsuda et al clarified the relationship between the appropriate shape of hollow fiber bundle and gas transfer rate of an outside blood flow membrane oxygenator by an experimental approach from a transport phenomenon perspective [ 12 , 13 ].…”

“…Numerous studies have been conducted on the design of membrane oxygenators [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. Matsuda et al clarified the relationship between the appropriate shape of hollow fiber bundle and gas transfer rate of an outside blood flow membrane oxygenator by an experimental approach from a transport phenomenon perspective [ 12 , 13 ]. On the other hand, a lot of knowledge has been obtained by Computational Fluid Dynamics (CFD) [ 14 , 16 , 17 , 18 ], Zhang et al developed the design methodology to optimize a design of membrane oxygenator by calculating blood velocity and pressure drop distributions in local areas inside a blood flow path using the CFD simulation [ 16 ].…”

Rearrangement of hollow fibers for enhancing oxygen transfer in an artificial gill using oxygen carrier solution

“…Several researchers have investigated the mass transfer correlations for membrane oxygenators [17][18][19][20][21][22][23][24][25][26][27][28][29][30], gas absorption modules [31][32][33], and other hollow fiber membrane devices [34][35][36][37][38][39]. Also, researchers in heat transfer have reported the heat transfer correlation for tube heat exchanger using tube bundle [40][41][42][43][44][45][46][47][48][49].…”

Mass Transfer in Blood Oxygenators Using Blood Analogue Fluids

“…The equivalent diameter, d , is defined as {4 × (volume of liquid)/(wetted surface area)}. Though this definition of the equivalent diameter strictly applies only to fully developed turbulent flow (22), it has been used by previous investigators when investigating mass transfer in BOs (23, 24). The volume of liquid in the module is given by while the wetted surface area is given by Thus the equivalent diameter is given by where ϵ is the void fraction, D 0 is the inside diameter of the module casing, D i is the outside diameter of the inner core, L 0 is the length of the module, L f is the total length of fibers present, and d 0 is the outside diameter of the fibers (see Figure 2).…”