Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages
Fatimah Almahasneh,
Ejlal Abu-El-Rub,
Ramada R Khasawneh
et al.
Abstract:BACKGROUND
Mesenchymal stem cells (MSCs) have been extensively studied for therapeutic potential, due to their regenerative and immunomodulatory properties. Serial passage and stress factors may affect the biological characteristics of MSCs, but the details of these effects have not been recognized yet.
AIM
To investigate the effects of stress factors (high glucose and severe hypoxia) on the biological characteristics of MSCs at different passages, in order to optimize the therape… Show more
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