Effects of high dose oral therapy with evening primrose oil in severe atopic dermatitis

Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials

“…3,4,26, Reference searching yielded four additional publications. [68][69][70][71] We excluded 14 publications for the following reasons: 13 publications addressed studies without a comparison group, [37][38][39][40][41][42][43][44][45][46][69][70][71] and one publication did not evaluate clinical outcomes of AD but only immunological outcomes. 47 Of the remaining 24 publications, two pairs were more or less exact copies describing two studies, 48-51 so that we ended up with 22 studies.…”

“…An initial literature search retrieved 34 publications of clinical studies 3,4 , 26,37–67 . Reference searching yielded four additional publications 68–71 .…”