Effects of high-dose folic acid on protein metabolism in breast muscle and performance of broilers

Liang, Saisai; Liu, Xinshuai; Zhao, Jingyuan; Li, Rui; Huang, Xinhuo; Li, Yanli; Yang, Xiaojun; Yang, Xin

doi:10.1016/j.psj.2022.101935

Cited by 6 publications

(3 citation statements)

References 45 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, folic acid is widely used in animal husbandry due to various important physiological functions. For instance, folic acid administration in the basal diet significantly increase the serum immunoglobulin content, reduce the serum cholesterol and improve the apparent digestibility of dry matter, crude protein, and crude fat of chickens ( 67 , 68 ). Moreover, folic acid supplementation can also improve the growth performance of piglets ( 69 ).…”

Section: Discussionmentioning

confidence: 99%

Complete genome analysis of Bacillus subtilis derived from yaks and its probiotic characteristics

Wang

Lin

et al. 2023

Front. Vet. Sci.

View full text Add to dashboard Cite

Probiotics have attracted attention due to their multiple health benefits to the host. Yaks inhabiting the Tibetan plateau exhibit excellent disease resistance and tolerance, which may be associated with their inner probiotics. Currently, research on probiotics mainly focuses on their positive effects on the host, but information regarding their genome remains unclear. To reveal the potential functional genes of Bacillus subtilis isolated from yaks, we sequenced its whole genome. Results indicated that the genomic length of Bacillus subtilis was 866,044,638 bp, with 4,429 coding genes. The genome of this bacteria was composed of one chromosome and one plasmid with lengths of 4,214,774 and 54,527 bp, respectively. Moreover, Bacillus subtilis contained 86 tRNAs, 27 rRNAs (9 16S_rRNA, 9 23S_rRNA, and 9 5S_rRNA), and 114 other ncRNA. KEGG annotation indicated that most genes in Bacillus subtilis were associated with biosynthesis of amino acids, carbon metabolism, purine metabolism, pyrimidine metabolism, and ABC transporters. GO annotation demonstrated that most genes in Bacillus subtilis were related to nucleic acid binding transcription factor activity, transporter activity, antioxidant activity, and biological adhesion. EggNOG uncovered that most genes in Bacillus subtilis were related to energy production and conversion, amino acid transport and metabolism, carbohydrate transport and metabolism. CAZy annotation found glycoside hydrolases (33.65%), glycosyl transferases (22.11%), polysaccharide lyases (3.84%), carbohydrate esterases (14.42%), auxiliary activities (3.36%), and carbohydrate-binding modules (22.59%). In conclusion, this study investigated the genome and genetic properties of Bacillus subtilis derived from yaks, which contributed to understanding the potential prebiotic mechanism of probiotics from the genetic perspective.

show abstract

Section: Discussionmentioning

confidence: 99%

Complete genome analysis of Bacillus subtilis derived from yaks and its probiotic characteristics

Wang

Lin

et al. 2023

Front. Vet. Sci.

View full text Add to dashboard Cite

show abstract

“…These findings suggested that protein in feed affects protein deposition in muscle. Studies have shown that activating the AKT/mammalian rapamycin (mTOR) pathway and increasing the phosphorylation activity of S6K1 can regulate protein deposition in muscle (Liang et al, 2022 ). Its protein complexes named mTOR C1 can then promote cell growth by inhibiting proteolytic metabolism, while amino acids stimulate the conversion of the regulator to an active nucleotide‐binding state, thereby allowing it to bind raptor and recruit mTOR C1 to the lysosomal surface (Saxton & Sabatini, 2017 ).…”

Section: Discussionmentioning

confidence: 99%

Exploring the effects of palm kernel meal feeding on the meat quality and rumen microorganisms of Qinghai Tibetan sheep

Raza

Gui

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

Palm kernel meal (PKM) has been shown to be a high‐quality protein source in ruminant feeds. This study focused on the effects of feed, supplemented with different amounts of PKM (ZL‐0 as blank group, and ZL‐15, ZL‐18, and ZL‐21 as treatment group), on the quality and flavor profile of Tibetan sheep meat. Furthermore, the deposition of beneficial metabolites in Tibetan sheep and the composition of rumen microorganisms on underlying regulatory mechanisms of meat quality were studied based on ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry as well as 16S rDNA sequencing. The results of the study showed that Tibetan sheep in the ZL‐18 group exhibited superior eating quality and flavor profile while depositing more protein and fat relative to the other groups. The ZL‐18 group also changed significantly in terms of the concentration and metabolic pathways of meat metabolites, as revealed by metabolomics. Metabolomics and correlation analyses finally showed that PKM feed mainly affected carbohydrate metabolism in muscle, which in turn affects meat pH, tenderness, and flavor. In addition, 18% of PKM increased the abundance of Christensenellaceae R‐7 group, Ruminococcaceae UCG‐013, Lachnospiraceae UCG‐002, and Family XIII AD3011 group in the rumen but decreased the abundance of Prevotella 1; the above bacteria groups regulate meat quality by regulating rumen metabolites (succinic acid, DL‐glutamic acid, etc.). Overall, the addition of PKM may improve the quality and flavor of the meat by affecting muscle metabolism and microorganisms in the rumen.

show abstract

“…Improvements in broiler genetics have led to significant advances in growth rates and efficiencies as well as carcass yield, but one consequence is that in some cases fat accumulation can be excessive ( Liang et al, 2022 ). Although abdominal fat is deposited later on in the life of the broiler ( Liu et al, 2023 ), the rate of fat accumulation increases in older birds to the point where it exceeds other components and reduces efficiency and relative value ( Wang et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of high-dose folic acid on protein metabolism in breast muscle and performance of broilers

Cited by 6 publications

References 45 publications

Complete genome analysis of Bacillus subtilis derived from yaks and its probiotic characteristics

Complete genome analysis of Bacillus subtilis derived from yaks and its probiotic characteristics

Exploring the effects of palm kernel meal feeding on the meat quality and rumen microorganisms of Qinghai Tibetan sheep

Age-associated changes in the growth development of abdominal fat and their correlations with cecal gut microbiota in broiler chickens

Contact Info

Product

Resources

About