Effects of High Calories High Protein Intake to Nitrogen Balance in end Stage of Nasopharyngeal Carcinoma Patient

Nuaba, I Gde Ardika; Dewi, Ni Ketut Kesuma

doi:10.13005/bpj/1334

Cited by 1 publication

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“…It has also been reported that home parenteral nutrition can support nitrogen balance in patients with inadequate calorie and protein intake [21]. High calorie and protein intake may improve nitrogen balance in end-stage nasopharyngeal carcinoma [22]. In a study by Geirsdottir et al, 70% of cancer patients had a negative nitrogen balance [23].…”

Section: Discussionmentioning

confidence: 99%

Comparison of per kilogram and nitrogen balance calculations for the prediction of daily protein requirement in cancer patients: A prospective randomized controlled study

Karakus,

Altinkaynak,

Akpinar

et al. 2023

Preprint

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Background & aims: Appropriate nutrition plan is required to fulfil the daily requirements in cancer patients. In this study, we aimed to compare the clinical and laboratory results of protein supplementation according to different calculation methods (per kg [PK] vs nitrogen balance equation [NBE]) in cancer patients. Methods: 103 cancer patients were included in this prospective randomized trial. Personalized diet lists were given to all patients according to their daily energy/protein requirements, where protein need was calculated with two different calculations: i) PK: 1.2-1.5 g/kg/day and ii) NBE. NBE was calculated with the net daily nitrogen losses from urine and faeces. Food consumption, and anthropometric, muscle function and laboratory measurements of the two groups were compared after 8 weeks. Daily 30 min brisk walking was planned for each patient. Results: 52 and 51 patients were included to PK and NBE groups (mean age: 50.9±11.1 and 53.1±12.3 years), respectively. After 8 weeks, the dietary compliance of the patients in PK and NBE groups were 93% and 95%. Daily protein intake was higher in the PK group. Both groups showed similar results regarding the lean body mass, muscle strength, walking speed and serum albumin. Gait speed was increased in both groups, and muscle strength was increased in the PK group. Conclusion: Protein supplementation according to both calculations provided comparable results in cancer patients. Personalized diet combined with moderate exercise improved the physical performance in both groups. Increased muscle strength in the PK group was associated with higher protein intake.

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Section: Discussionmentioning

confidence: 99%