Effects of heat stress on muscle mass and the expression levels of heat shock proteins and lysosomal cathepsin L in soleus muscle of young and aged mice

Effects of Catechin-Ingestion and Heat Stress on the Maximum Isometric Force in Knee Extension, the Volume of Quadriceps Muscle, and Serum Thiobarbituric Acid Reactive Substances Level in Healthy Elderly Women

“…There is no report regarding the effects of heat stress on skeletal muscle in female animals and human subjects. Although we confirmed heat stress-associated muscle hypertrophy in aged mice recently [19], it is still unclear the effects of heat stress on skeletal muscle function in healthy elderly women.…”

“…It has been proposed that heat stress may be a countermeasure for prevention of muscle atrophy [18]. Recently, heat stress-associated skeletal muscle hypertrophy has been reported in aged (106-week old) mice [19]. These evidences strongly suggested that the application of heat stress could induce muscular hypertrophy and could improve muscle function in elderly people.…”

Stress Effects on Meat Quality: A Mechanistic Perspective

“…Belcastro, Shewchuk, and Raj () indicated that intense or exhaustive exercise can stimulate cathepsin D in mammalian muscle. Heat stress significantly decreased cathepsin L expression in skeletal muscle of aged mice, indicating its potential role in mediating muscle hypertrophy (Ohno et al., ). Bahuaud et al.…”

“…Belcastro, Shewchuk, and Raj (1998) indicated that intense or exhaustive exercise can stimulate cathepsin D in mammalian muscle. Heat stress significantly decreased cathepsin L expression in skeletal muscle of aged mice, indicating its potential role in mediating muscle hypertrophy (Ohno et al, 2012). Bahuaud et al (2010) indicated that preslaughter stress, including crowding, chasing, and noisy environments, also led to the increased expression and enhanced activity of cathepsin B and L in farmed Atlantic salmon fillets, which resulted in a faster degradation of muscle proteins and impaired textural properties.…”

Differential levels of cathepsin B and L in serum between young and aged healthy people and their association with matrix metalloproteinase 2

“…In this study, we found that the serum level of cathepsin B had a downward trend with age, but remained no significant difference between young and aged groups, while cathepsin L significantly decreased with age. Research conducted by Ohno et al (2012) shows that significant decrease in cathepsin L expression by heating was observed in aged soleus, but not in young mice. The serum level of cathepsin B remained no significant difference between young and aged groups may be due to the aged group in our study was not old enough.…”