Effects of halothane on coronary and systemic circulations, myocardial metabolism and blood flow distribution within the canine heart.

Enflurane-Induced Hypotension Modifies Transmural Blood Flow Distribution in the Canine Left Ventricle

“…The authors have reported on changes in I/O ratio during light to deep halothane anesthesia (Saito et al 1977). The ratio was well maintained near 1.0 as was in the control state even after 3 hr successive inhalation of three different concentrations of halothane for 1 hr each (1, 1.5 and 2% halothane).…”