Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women

Abstract

Grape seed proanthocyanidin extract is effective in improving the physical and psychological symptoms of menopause while increasing muscle mass and reducing blood pressure in middle-aged women.

Bioavailability of wild blueberry (poly)phenols at different levels of intake

“…Although there is scientific evidence showing that different (poly)phenol levels can affect the magnitude of health outcomes [12,[24][25][26][27][28][29], most of these studies included only two levels of (poly)phenol amounts, limiting the evaluation of dose-response relationships. Furthermore, most studies highlight the health benefits without investigating (poly)phenol bioavailability in a dose-response manner, so it is crucial to understand how (poly)phenol dosage can affect the metabolism and disposition of these compounds in humans.…”

Prevalence and predictors of storage lower urinary tract symptoms in perimenopausal and postmenopausal women attending a menopause clinic

“…The MHR-QOL, developed and validated in our clinic, [26][27][28][29][30][31][32]34 is a modification of the Women's Health Questionnaire 35,36 and contains 38 items scored on a four-point or binary scale covering four major domains of a woman's health during menopause (physical health, mental health, life satisfaction, and social involvement). The physical health domain consists of nine items that assess vasomotor, somatic, and urinary symptoms, including frequent urination.…”

Subjective insomnia is associated with low sleep efficiency and fatigue in middle-aged women

“…The MHR-QOL questionnaire, developed and validated at our clinic 16,17 , is a modification of the Women's Health Questionnaire 18,19 and contains 38 items scored on a four-point or binary scale covering four major domains (physical symptoms, psychological symptoms, life satisfaction, and social involvement) of a woman's health during menopause. The HADS, developed by Zigmond and Snaith 20 , is a reliable instrument for screening clinically significant anxiety and depression in women visiting a general medicine clinic; it was translated into Japanese by Kitamura and colleagues 21 .…”

“…The HADS, developed by Zigmond and Snaith 20 , is a reliable instrument for screening clinically significant anxiety and depression in women visiting a general medicine clinic; it was translated into Japanese by Kitamura and colleagues 21 . Detailed information about the MHR-QOL questionnaire and the HADS is provided elsewhere 16 .…”

“…Each item of the AIS can be rated 0-3 (0, no problem at all; 3, a very serious problem) and the sum of the score of eight items ranging from 0 to 24 is shown as the AIS score. A total score of 6 is regarded as the optimum cut-off for a diagnosis of insomnia 15,16 .…”