Effects of Gonadal Hormones on Plasma Renin Activity and Aldosterone Excretion Rate

Crane, Milton G.; Harris, Jennifer

doi:10.1007/978-1-4684-1782-1_32

Cited by 52 publications

(64 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Plasma renin activity and aldosterone secretion both diminish with age, as does the ability to respond to sodium deprivation with an appropriate increase in renin and aldosterone secretion (81). On the other hand, levels of plasma antidiuretic hormone (ADH) or arginine vasopressin (AVP) are elevated in older persons with dehydration compared to younger persons (78,82), indicating that this portion of the volume and tonicity defence mechanism is not reduced with ageing.…”

Section: Etiology Of Dehydration In Older Personsmentioning

confidence: 99%

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

Raman

Pal

Ganesan

et al. 2016

Eye

View full text Add to dashboard Cite

Section: Etiology Of Dehydration In Older Personsmentioning

confidence: 99%

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

Raman

Pal

Ganesan

et al. 2016

Eye

View full text Add to dashboard Cite

“…The age related fall in supine and ambulant plasma aldosterone is well established 4,6,7,35 but the etiology is less clear. We have documented a severely impaired aldosterone response to Hypertensin in the older subjects, despite similar plasma Hypertensin levels.…”

Section: 28mentioning

confidence: 99%

Aging and Human Hormonal and Pressor Responsiveness to Angiotensin II Infusion With Simultaneous Measurement of Exogenous and Endogenous Angiotensin II

Duggan

Nussberger

Kilfeather

et al. 1993

American Journal of Hypertension

View full text Add to dashboard Cite

] ANG II in plasma by using isocratic HPLC and radioimmunoassays with cross-reacting antibodies and compared re sults with immunoreactive ANG II which was mea sured conventionally using monoclonal antibodies.Baseline endogenous ANG II (AspSlle^ANG II) levels in venous plasma were marginally, but not significantly, lower in the old [mean (95% confi dence limits): 3.4 «0.1 to 7.7) ν 3.7 (1.2 to 6.2), fmol/ mL] and during suppression by the Hypertensin in fusion appeared consistently, but not significantly, lower in the old [0.9 (0 to 3.1) ν 2.1 (0.6 to 3.7), after 3 ng/kg/min], while the same infusion rate in young and old resulted in similar plasma Hypertensin levels. Baseline systolic blood pressure (SBP) was similar in both groups but the percentage increases in SBP at infusion rates of 1, 3.0, and 10 ng/kg/min were greater in the old than in the young (9.1 ν 2.8, Received October 15, 1992. Accepted April 13, 1993.

show abstract

“…In normotensive adults, there is generally no sex difference; however, Tan and co-workers (1978) have reported that women have lower values than age-matched men. Various studies of age effects have shown either no significant change in plasma renin activity with age (Karlberg and Tolagen, 1977), or more commonly a decrease with age, especially after the fourth decade (Crane and Harris, 1976;Vetter et aI., 1976;Salvetti et aI., 1977;Tan et aI., 1978).…”

Section: Renin and Aldosteronementioning

confidence: 99%

Genetic and familial factors in essential hypertension and related traits

Siervogel

1983

American J Phys Anthropol

View full text Add to dashboard Cite

The health significance of essential hypertension (high blood pressure of undefined origin) is well established. It is a major factor contributing to coronary heart disease, stroke, and kidney failure. It directly affects about one in five Americans. Factors which are known to be associated with blood pressure include: body composition as it relates to overall mass and fat mass; physiological variables involving the sympathetic and parasympathetic nervous systems; biochemical variables such as renin, aldosterone, kallikrein, lipids, and lipoproteins, etc.; environmental variables such as sodium intake, heavy metals, and noise; and psychological variables involving personality type and mental stress.There is a definite, well-established genetic involvement in hypertension, but specific genetic mechanisms remain a mystery. Familial aggregation occurs for many of the associated traits listed above. For some, specific polymorphic major genes have been identified, but for others genetic factors are unidentified. Essential hypertension is undoubtedly a heterogeneous group of diseases with the common end result of elevated blood pressure. Because of its health significance, there is considerable interest in identifying genetic mechanisms resulting in essential hypertension. One area that currently shows some potential for the identification of a specific genetic mechanism is related to the transmembrane transport of sodium and potassium cations.A genetic component has long been suspected in essential hypertension, but a clear and definitive genetic mechanism has yet to be identified. Since there are many variables that can affect blood pressure, this review of the genetics of essential hypertension necessarily involves a discussion of related traits. Before focusing on the genetic and familial aspects of hypertension a description of the normal course of human blood pressure is presented and some of the traits related to it are discussed. NATURAL HISTORY OF BLOOD PRESSUREUntil recently, reports describing blood pressure patterns during the neonatal period were relatively few, largely because of the difficulty of accurately measuring blood pressure in infants by noninvasive techniques. The ultrasonic technique utilizing the Doppler effect greatly facilitated noninvasive systolic blood pressure determination in infants (McLaughlin et al., 1971). Accurate automatic methods are currently available using the oscillometric principal coupled with a microcomputer and a standard limb blood presure cuff (Friesen and Lichtor, 1981). Even in adults newer methods are being developed (Wolthuis et al., 1981).© 1983 Alan R. Liss, Inc. [Vol.26,1983 Systolic blood pressure tends to increase sharply during the first two weeks of life from a mean of 70 mmHg at 2 days to 84 mmHg at 2 weeks. It continues to increase at a slightly slower rate over the next 4 weeks to a mean of about 93 mmHg at 6 weeks (Earley et aI., 1980); from 6 weeks to 1 year af age there is little change in systolic pressure (deSwiet et aI., 1975(deSwiet et ...

show abstract

Effects of Gonadal Hormones on Plasma Renin Activity and Aldosterone Excretion Rate

Cited by 52 publications

References 10 publications

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

Aging and Human Hormonal and Pressor Responsiveness to Angiotensin II Infusion With Simultaneous Measurement of Exogenous and Endogenous Angiotensin II

Genetic and familial factors in essential hypertension and related traits

Contact Info

Product

Resources

About