Effects of gestational diabetes mellitus on time to delivery and pregnancy outcomes in full-term pregnancies with dinoprostone labor induction

Jiang, Tingting; Zhao, Lei; Lin, Yu-Cheng; Zhou, Dong; Wang, Ling; Sun, Guoqiang; Xiao, Mei

doi:10.1080/10641963.2018.1441859

Cited by 7 publications

(10 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In patients without contractions, we found that the rate of vaginal delivery was increased significantly at 39–39 + 6 gestational weeks when given iatrogenic intervention, but there were no differences in the vaginal delivery rate at 40–40 + 6 gestational weeks. This is the same with a study involving Chinese pregnant women on induction of labor with dinoprostone in a patient with GDM [ 25 ]. Therefore, we recommend that iatrogenic intervention be performed at 39–39 + 6 weeks of gestation to induce labor.…”

Section: Discussionsupporting

confidence: 76%

Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study

Yin

Zhang

et al. 2022

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

Background To determine the optimal delivery time for women with diet-controlled gestational diabetes mellitus by comparing differences in adverse maternal–fetal outcome and cesarean section rates. Methods This real-world retrospective study included 1,050 patients with diet-controlled gestational diabetes mellitus who delivered at 35–42 weeks’ gestation. Data on patient characteristics, maternal–fetal outcomes, and cesarean section rate based on fetal gestational age were collected and analyzed. Differences between deliveries with and without iatrogenic intervention were also analyzed. Results The cesarean section rate at ≥ 41 weeks’ gestation was significantly higher than that at 39–39 + 6 weeks (56% vs. 39%, p = 0.031). There were no significant differences in multiple adverse maternal or neonatal outcomes at delivery before and after 39 weeks. Vaginal delivery rates were increased significantly at 39–39 + 6 weeks due to iatrogenic intervention (p = 0.005) and 40–40 + 6 weeks (p = 0.003) in patients without and with spontaneous uterine contractions, respectively. Conclusions It’s recommended that optimal delivery time for patients with diet-controlled gestational diabetes mellitus should be between 39- and 40 + 6 weeks’ gestation. Patients who have Bishop scores higher than 4 can undergo iatrogenic intervention at 39–39 + 6 weeks. However iatrogenic interventions are not recommended for patients with low Bishop scores.

show abstract

Section: Discussionsupporting

confidence: 76%

Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study

Yin

Zhang

et al. 2022

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

“…In 2017, the obstetricians in Hubei Province of China had evaluated the use of Dinoprostone, and revealed that the vaginal delivery rate of those using Dinoprostone was higher than that of the entire year. It was safe to use Dinoprostone in Chinese population, even in some subgroups of patients with gestational diabetes mellitus (GDM) or hypertension (18,19). The effectiveness and safety of Dinoprostone and doubleballoon catheter stratified by Bishop score were not reported.…”

Section: Discussionmentioning

confidence: 99%

Comparing the effectiveness and safety of Dinoprostone vaginal insert and double-balloon catheter as cervical ripening treatments in Chinese patients

Yan

Yin

2022

Front. Med.

View full text Add to dashboard Cite

BackgroundThis retrospective study was to compare the effectiveness and safety of Dinoprostone vaginal insert vs. double-balloon catheter as cervical ripening agents for labor induction.MethodsPregnant women with Bishop score <7, who received either Dinoprostone vaginal insert 10 mg or Cook's double-balloon catheter for labor induction, were studied. The primary outcome was the rate of vaginal delivery within 48 h; the secondary outcomes were the proportion of women undergoing cesarean section, labor duration, oxytocin administration, changes in Bishop score, complications during labor, and maternal/neonatal outcomes.ResultsOne hundred and eighty-two women were included in Dinoprostone group, and 199 women were in double-balloon catheter group. The rate of vaginal delivery within 48 h was significantly higher in Dinoprostone group than that in double-balloon catheter group (90.11% vs. 75.38%, P = 0.0002). There were 18 cesarean section deliveries (9.89%) in Dinoprostone group and 49 cesarean section deliveries (24.62%) in double-balloon catheter group, with significant differences between two groups (P = 0.0002). The duration of labor was higher in Dinoprostone group, while the augmentation with oxytocin was significantly lower in Dinoprostone group than in double-balloon catheter group (all P < 0.0001). The incidence of chorioamnionitis was significantly higher in double-balloon catheter group as compared with Dinoprostone group (0 vs. 12, P = 0.0005), while neonatal outcomes were similar in two groups.ConclusionDinoprostone vaginal insert as cervical ripening agent is more effective for labor induction and with lower risks of chorioamnionitis as compared with double balloon catheter in Chinese populations.

show abstract

“…A study by Feleke et alalso showed the association of GDM with a history of abortion, and reported that abortion increases the risk of GDM in the future pregnancies. In his study, the chances of GDM in women with a history of abortion were 5 times higher [ 32 ], which may be due to the effect of abortion on impaired normal insulin metabolism in women [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery among pregnant women: a national prevalence study of 11 provinces in Iran

Darbandi,

Rezaeian,

Dianatinasab

et al. 2022

Journal of Preventive Medicine and Hygiene

View full text Add to dashboard Cite

Summary Background Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy that significantly affects perinatal outcomes. Objective The aim of this study was to determine the prevalence of GDM and its relation with the incidence of stillbirth, preterm birth, macrosomia, abortion and cesarean section (C-section) delivery in pregnant women. Methods This cross-sectional study was conducted on 3675 pregnant women in 11 provinces across Iran. Cluster sampling was used to select samples from mothers covered by health plans in 11 provinces of Iran. Prevalence of adverse pregnancy outcomes, including preterm delivery, type of delivery, macrosomic preterm birth, miscarriage, stillbirth, infant death, and birth weight were measured, using family record and face-to-face interviews. Data were analyzed by logistic regression, using STATA14.2 software. Results About four percent of Iranian pregnant women had GDM during pregnancy. Prevalence of C-section was significantly higher in diabetic women than in the non-diabetic ones (53.19 vs 46.81, respectively, P < 0.001). Abortion in diabetic mothers was more than twice that of the non-diabetic mothers (P < 0.001). In the adjusted logistic regression model, the odds of stillbirth in mothers with GDM were 1.8 (95% CI: 1.11, 2.91, P = 0.018) times higher than that of the non-diabetics. The odds of macrosomia in diabetic women was about 7 times higher than the non-diabetic women (95% CI: 2.81, 17.14, P < 0.001). The odds of GDM had an increasing trend according to the BMI (p < 0.001). The risk of GDM were significantly lower, according to the daily physical activity (PA) (p < 0.001). Conclusion The GDM prevalence has a decreasing trend in Iran. It increases the adverse pregnancy outcomes such as stillbirth, neonatal deaths, macrosomia, preterm birth, abortion and C-section delivery. As, some of these consequences like macrosomia are not treatable, thus early prevention is very crucial.

show abstract

Effects of gestational diabetes mellitus on time to delivery and pregnancy outcomes in full-term pregnancies with dinoprostone labor induction

Abstract: GDM did not affect the time to delivery, cesarean delivery and other perinatal outcomes in Chinese women underwent dinoprostone-induced labor. However, it may be associated with the lower rates of delivery within different time intervals.

Cited by 7 publications

References 27 publications

Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study

Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study

Comparing the effectiveness and safety of Dinoprostone vaginal insert and double-balloon catheter as cervical ripening treatments in Chinese patients

Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery among pregnant women: a national prevalence study of 11 provinces in Iran

Contact Info

Product

Resources

About