Effects of General-epidural Anaesthesia on the Hemodynamics in Patients with Myasthenia Gravis

Xz, Liu; Cw, Wei; Hy, Wang; Yh, Ge; Chen, J; Wang, J; Zhang, Y

doi:10.7727/wimj.2013.054

Cited by 3 publications

(1 citation statement)

References 18 publications

(10 reference statements)

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“…In the present study, patients undergoing CGEA took less time than those undergoing TIVA to recover spontaneous breathing, open their eyes on hearing whispered words and for tracheal extubation. Consistent with the current findings, Liu et al ( 41 ) demonstrated that the CGEA group had a shortened postoperative extubation time and recovery duration than the TIVA group. CGEA was reported to have the advantages of maintaining a normal hormone level, controlling blood pressure, maintaining hemodynamics and requiring less medication ( 42 – 44 ).…”

Section: Discussionsupporting

confidence: 91%

Effects of combined general-epidural anesthesia and total intravenous anesthesia on cellular immunity and prognosis in patients with non-small cell lung cancer: A comparative study

Shi

Zhang

et al. 2017

Molecular Medicine Reports

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The aim of the present study was to investigate the effects of combined general-epidural anesthesia (CGEA) and total intravenous anesthesia (TIVA) on cellular immunity and prognosis in patients with non-small cell lung cancer (NSCLC) in a Chinese population. One-hundred and twenty NSCLC patients were randomly divided into a TIVA group (n=60) and a CGEA group (n=60) using a random number table. All patients underwent video-assisted thoracoscopic surgery for radical resection. Blood pressure (BP) and peripheral oxygen saturation (SpO2) were measured. Post-operative analgesic effects were evaluated with a visual analog scale pain score. Flow cytometry was applied to measure T lymphocyte subsets [cluster of differentiation (CD)3+, CD4+, CD8+ and CD4+/CD8+] and natural killer cell CD56+. A 3-year follow-up was conducted to observe the prognosis. The analgesic effects of CGEA were identified to be better than those of TIVA. Compared with the TIVA group, the CGEA group demonstrated a shorter time of spontaneous breathing recovery, eyes opening, and extubation, lower heart rate, blood pressure and mean arterial pressure, and higher SpO2. At 24 and 48 h after surgery, CD3+, CD4+, CD4+/CD8+ and CD56+ in the CGEA group were higher than those in the TIVA group. At 72 h after surgery, CD3+, CD4+, CD4+/CD8+ in the CGEA group were higher than those in the TIVA group. These results indicate that CGEA and TIVA effected cellular immunity, and CGEA had a reduced effect on cellular immunity and improved postoperative analgesic effects.

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Section: Discussionsupporting

confidence: 91%