Effects of Gaseous Distention on Obstructed Bowel

Effects of Distension and Acetylcholine on Intestinal Blood Flow <i>in vivo</i>

“…However, there is apparently a dis crepancy between our present results and those of P r ic e et al [11], who described an enhancement of mesenteric blood flow upon passive gut distension with saline. Parenthetically, it should be noted that the effects of distension whether with saline [1,3,4,7,15] or air [6,14] do not seem to differ as far as diminishing blood flow is concerned. Nevertheless, despite the difference in reported results of enhanced blood flow [11] and reduced blood flow [1,3,4,6,7,8,9,14,15] upon gut distension, there appear to be reasonable explanations.…”

“…Parenthetically, it should be noted that the effects of distension whether with saline [1,3,4,7,15] or air [6,14] do not seem to differ as far as diminishing blood flow is concerned. Nevertheless, despite the difference in reported results of enhanced blood flow [11] and reduced blood flow [1,3,4,6,7,8,9,14,15] upon gut distension, there appear to be reasonable explanations. In the experiments by P r ic e et al [11], blood flow of the entire small intestine was measured, whereas the other authors [1,3,4,[6][7][8][9]15] and we recorded only flow to or from a segment with a circum scribed blood supply.…”

Transmesenteric Hernia in a Peripartum Patient: An Unusual Diagnosis

“…Treves described a similar condition in the mesentery of the ileocolic region [11]. The mechanism of the development of transmesenteric hernia is by gas trap theory, where a portion of bowel passes through the defect and by peristalsis and production of gas more bowel loops is drawn through the aperture, leading to incarceration [12].…”

The effect of distention on blood flow through the intestine.

“…There is also universal agreement that distention of the gut under excessive pressures decreases the intestinal blood flow (S, 10,11,12). Attention has for the most part, however, been directed to the effect of pressures approaching the level of mean arterial pressure, which are considerably higher than the pressures usually observed in obstructed intestine.…”