Effects of gallic acid on the morphology and growth of hydroxyapatite crystals

Tang, Bei; He, Yuanqing; Cheng, Lei; Zhou, Xuedong; Huang, Xuelian; Li, Jiyao

doi:10.1016/j.archoralbio.2014.09.011

Cited by 31 publications

(27 citation statements)

References 18 publications

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“…The presence of the strongest peak at 1021 cm −1 and the band appearing at 1091 cm −1 were due to the P=O stretching vibration of phosphate groups. Additionally, the peak at 960 cm −1 was ascribed to the phosphate group , . Peaks that characterize HAP crystals were detected in all FTIR spectra of the crystals obtained in the presence of the additive.…”

Section: Resultsmentioning

confidence: 99%

Characteristics and Thermal Kinetics of Hydroxyapatite Crystals Doped with Tricarballylic Acid

Polat

2018

Chem Eng & Technol

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Hydroxyapatite (HAP) has attracted interest in many fields, e.g., catalysis, water treatment processes, and pharmaceutical industries. HAP crystallization was performed within a batch‐type crystallizer both with and without tricarballylic acid used as additive. The crystals produced in pure media and in the presence of tricarballylic acid were characterized and their thermal degradation was then accomplished in a thermal analyzer in an inert atmosphere. Experimental data was used to calculate the activation energies based on the Kissinger, Flynn‐Wall‐Ozawa, Kissinger‐Akahira‐Sunose, and Starink kinetic models. The results revealed that tricarballylic acid was adsorbed onto the crystal surface, with significant effects on crystal morphology, thermal degradation behavior, and average activation energy.

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Section: Resultsmentioning

confidence: 99%

Characteristics and Thermal Kinetics of Hydroxyapatite Crystals Doped with Tricarballylic Acid

Polat

2018

Chem Eng & Technol

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“…GA seemed to be the main active ingredient in mineralization [Huang et al, 2012]. Numerous findings, either qualitative or quantitative, have supported the remineralization properties of the G. chinensis compounds, and a mechanism of action has been speculated as interacting with enamel organic matrix to promote the mineral deposition [Zhang et al, 2009a;Cheng and ten Cate, 2010;Tang et al, 2015].…”

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confidence: 89%

<b><i>Galla chinensis </i></b>Compounds Remineralize Enamel Caries Lesions in a Rat Model

et al. 2016

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Objectives: To investigate the effect of Galla chinensis chemical compounds on enamel caries remineralization in rats. Methods: A total of 40 rats were inoculated with Streptococcus sobrinus 6715 and fed a cariogenic diet (Keyes 2000). The rats were randomly divided into 4 groups and treated topically twice a day with each of the following extracts (or control) for 5 weeks: distilled and deionized water (DDW, negative control); 1,000 ppm NaF (positive control); 4,000 ppm G. chinensis crude aqueous extract (GCE), or 4,000 ppm gallic acid (GA). After the experimental period, Keyes' caries diagnosis and scoring technique was applied as a preliminary evaluation on the molar teeth. For more accurate remineralization data, the residual enamel volume of the first molar and the mineral density (MD) of the enamel were further analyzed by micro-CT. Results: The severity of molar enamel caries decreased in the following order of treatment groups: DDW > GA > GCE > NaF (p < 0.05). In addition, the residual first molar enamel volume and MD values increased in the order of DDW, GA, GCE and NaF treatment groups (p < 0.05). In most molars, remineralization layers were observed on the surface of lesions. Conclusion:G. chinensis compounds remineralize enamel caries lesions in a rat model.

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“…Gallic acid is one promising component isolated from galla chinensis, but the action modes were different between GCE and gallic acid. Tang et al [2015] made a further investigation on the effect of gallic acid on the morphology and growth of hydroxyapatite crystals. Thus, it implied that the crude extract of galla chinensis might have several effective components which showed combined effects on the regulation of the de-/remineralization balance.…”

Section: Resultsmentioning

confidence: 99%

“…So it explains why remineralization was more obvious in the lesion body. Another investigation indicated that gallic acid affects and participates in the formation of hydroxyapatite, and regulates the morphology and structure of the crystals, to enhance the remineralization process [Tang et al, 2015].…”

Section: Galla Chinensismentioning

confidence: 99%

Natural Products and Caries Prevention

Cheng

et al. 2015

Caries Res

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Dental caries is considered as the most common polymicrobial oral disease in the world. With the aim of developing alternative approaches to reduce or prevent the decay, numerous papers showed the potential anticaries activity of a number of natural products. The natural products with anticaries effects are selected from e.g. food, beverages, flowers or traditional herbs. Most of the effective components are proven to be polyphenol compounds. Many of the natural products are studied as antibacterial agents, while some of them are found to be effective in shifting the de-/remineralization balance. However, the mechanisms of the anticaries effects are still unclear for most of the natural products. In the future, more efforts need to be made to seek novel effective natural products via in vitro experiment, animal study and in situ investigations, as well as to enhance their anticaries effects with the help of novel technology like nanotechnology.

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Effects of gallic acid on the morphology and growth of hydroxyapatite crystals

Cited by 31 publications

References 18 publications

Characteristics and Thermal Kinetics of Hydroxyapatite Crystals Doped with Tricarballylic Acid

Characteristics and Thermal Kinetics of Hydroxyapatite Crystals Doped with Tricarballylic Acid

<b><i>Galla chinensis </i></b>Compounds Remineralize Enamel Caries Lesions in a Rat Model

Natural Products and Caries Prevention

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