Effects of frequent ultrasound during pregnancy: a randomised controlled trial

Newnham, John P.; Evans, Sharon F.; Michael, C.A.; Stanley, F.J.; Landau, Louis I.

doi:10.1016/0140-6736(93)91944-h

Cited by 587 publications

(449 citation statements)

References 16 publications

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“…These observational cohort studies investigated women from Mississippi and pregnancies from the Western Australian pregnancy cohort that assessed the effects of a single vs multiple ultrasounds on antepartum, intrapartum, postpartum and neonatal outcomes, 8 and that study had been approved by the Ethics Committee at King Edward Memorial Hospital, Subiaco, Western Australia. The patients were recruited from consecutive women presenting to the ultrasound units for a fetal anatomic survey in the second trimester of pregnancy and are representative of the women managed at each respective medical center.…”

Section: Methodsmentioning

confidence: 99%

“…All placenta previas, partial previas and low implantation sites were analyzed with both abdominal and vaginal ultrasounds and reanalyzed in the third trimester of pregnancy to determine if the initial implantation site had migrated. In all analyses, the 10 placental locations were initially categorized into four groups (low 1: low central (0), right low (8) and left low (9); low 2: low 6 and post low 7; high lateral: left high 2 and right high 3; and high fundal: fundal (1), ant high 4, post high 5, where the high 2 was the reference group selected as the most common). For analysis purposes, groups low 1 and low 2 were combined into one category because of very low rate of the group low 1 encountered (only two cases in the Mississippi data set and 16 cases in the Western Australia dataset), resulting in a low group, high lateral and high fundal.…”

Section: Methodsmentioning

confidence: 99%

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Second trimester placental location as a predictor of an adverse pregnancy outcome

et al. 2006

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Objective: To determine if the second trimester placental location is associated with perinatal outcomes. Materials and methods:Observational study of placental location and the subsequent risk of an adverse pregnancy outcome. Placental location was divided into three categories, low, high lateral and high fundal.Results: There were 3336 pregnancies analyzed in this study. Low implantation sites had a greater risk of preterm labor (odds ratio (OR) 1.70, 95% confidence interval (CI) 1.38 to 2.90, P<0.001), preterm delivery (OR 1.86, 95% CI 1.36 to 2.54, P<0.001), fewer fetuses with macrosomia (OR 0.56, 95% CI 0.38 to 0.83, P ¼ 0.010) and reduced risk of postpartum hemorrhage (OR 0.56, 95% CI 0.46 to 0.95, P ¼ 0.026). High lateral implantations had a greater risk of low 1-min (OR 1.80, 95% CI 1.11 to 2.93, P ¼ 0.017) and 5-min (OR 3.49, 95% CI 1.46 to 8.36, P ¼ 0.005) Apgar scores.Conclusions: Low placental implantation was associated with an increased risk of preterm labor, preterm delivery and a reduced risk of postpartum hemorrhage, and of a macrosomic fetus. High lateral implantation was associated with low Apgar scores.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Second trimester placental location as a predictor of an adverse pregnancy outcome

et al. 2006

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“…In the Western Australian Pregnancy Cohort (Raine) Study researchers are following a cohort born between 1989 and 1991 (Newnham, Evans, Michael, Stanley, & Landau, 1993). Motor performance was assessed at 10, 14 and 17 years of age using the MAND (McCarron, 1997).…”

Section: Introductionmentioning

confidence: 99%

The psychometric properties of the McCarron Assessment of Neuromuscular Development as a longitudinal measure with Australian youth

Hands

Larkin

Rose

2013

Human Movement Science

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This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues.Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. b s t r a c tThe importance of considering age and sex differences in the assessment of motor performance has been largely overlooked. This study examines the psychometric properties of the US developed McCarron Assessment of Neuromuscular Development (MAND) using data from a longitudinal sample of 986 Australian youth at 10, 14 and 17 years. A key finding was the sex and age interaction of the Neuromuscular Developmental Index (NDI) (F = 121.46, p < .001). Males had a significantly lower mean NDI score at 10 years and the females had a lower score at 17 years. The factor structure differed from the US samples (McCarron, 1997) at each age and between males and females. The sex specific analyses showed that the underlying structure was more complex for younger females. Although the MAND remains a useful test of motor performance for Australian children, further consideration is warranted regarding sex differences, the relevance of the US based normative tables and factor structures.

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“…Further, the investigated SNPs could be in linkage disequilibrium (LD) with other as yet unidentified causal variants, and this will be a focus of future studies using efficient next-generation sequencing strategies. Strengths of our study include a large homogeneous study population, assessment of both maternal and adolescent data, a relatively high attendance at cohort follow-ups, inclusion of fasting blood samples, standardized endpoint measurements and an accurate diagnosis of preeclampsia [21].…”

Section: Discussionmentioning

confidence: 99%

“…The study has been described in detail elsewhere [21]. Pregnant women (n = 2,900) were enrolled between August 1989 and April 1992, and they gave birth to 2,868 live babies.…”

Section: Study Populationmentioning

confidence: 99%

Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22

Løset

Johnson

Melton

et al. 2014

Pregnancy Hypertension: An International Journal of Women's Car

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Objective: Four putative single nucleotide polymorphism (SNP) risk variants at the preeclampsia susceptibility locus on chromosome 2q22; rs2322659 (LCT), rs35821928 (LRP1B), rs115015150 (RND3) and rs17783344 (GCA), were recently shown to associate with known cardiovascular risk factors in a Mexican American cohort. This study aimed to further evaluate the pleiotropic effects of these preeclampsia risk variants in an independent Australian population-based cohort. Methods:The four SNPs were genotyped in the Western Australian Pregnancy Cohort (Raine) Study that included DNA, clinical and biochemical data from 1,246 mothers and 1,404 of their now adolescent offspring. Genotype association analyses were undertaken using the SOLAR software.Results: Nominal associations (P < 0.05) with cardiovascular risk factors were detected for all four SNPs. The LCT SNP was associated with decreased maternal height (P = 0.005) and decreased blood glucose levels in adolescents (P = 0.022). The LRP1B SNP was associated with increased maternal height (P = 0.026) and decreased maternal weight (P = 0.044). The RND3 SNP was associated with decreased triglycerides in adolescents (P = 0.001). The GCA SNP was associated with lower risk in adolescents to be born of a preeclamptic pregnancy (P = 0.003) and having a mother with prior preeclamptic pregnancy (P = 0.033). Conclusions:Our collective findings support the hypothesis that genetic mechanisms for preeclampsia and CVD are, at least in part, shared, but need to be interpreted with some caution as a Bonferroni correction for multiple testing adjusted the statistical significance threshold (adjusted P < 0.001).

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Effects of frequent ultrasound during pregnancy: a randomised controlled trial

Cited by 587 publications

References 16 publications

Second trimester placental location as a predictor of an adverse pregnancy outcome

Second trimester placental location as a predictor of an adverse pregnancy outcome

The psychometric properties of the McCarron Assessment of Neuromuscular Development as a longitudinal measure with Australian youth

Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22

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