Effects of Four Intravenous Anesthetic Agents on Motor Evoked Potentials Elicited by Magnetic Transcranial Stimulation

Nadstawek, J.; Taniguchi, Makoto; Langenbach, Ulrich; Bremer, F

doi:10.1097/00000542-199209001-00500

Cited by 4 publications

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“…bolus of thiopentone 250 mg induced a marked reduction in amplitude of MEP by transcranial electrical stimulation in comatose patients. Nadstawek Taniguchi and Bremer [8] demonstrated that MEP elicited by transmagnetic stimulation disappeared completely during continuous infusion of thiopentone producing very light anaesthesia in 12 of 15 patients. In the present study MEP recording during administration of thiopentone was feasible only with a minimum dose.…”

Section: Discussionmentioning

confidence: 99%

“…Both techniques make it possible to evoke motor responses in various muscles of the upper and lower limbs and of the face. However, anaesthetic agents may interfere with the reproducibility of such responses and limit the usefulness of this technique [3,[6][7][8].…”

mentioning

confidence: 99%

“…Several authors have demonstrated the effects of thiopentone on SEP and MEP [7,8,[12][13][14][15][16], but there are no data on the minimum dose of thiopentone for successful recording of MEP during high-dose barbiturate therapy. Therefore, we have evaluated the effect of thiopentone on MEP induced by transcranial magnetic stimulation.…”

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confidence: 99%

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Effect of Thiopentone on Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation in Humans

Kawaguchi

Sakamoto

Shimizu

et al. 1993

British Journal of Anaesthesia

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We have studied the effect of repeated doses of thiopentone on motor evoked potentials (MEP) after transcranial magnetic stimulation in 13 patients. Thiopentone was administered i.v. in an initial dose of 2 mg kg-1, followed by repeated doses (1 mg kg-1 every 3 min) until the appearance of burst suppression on the EEG. The total dose administered was mean 10.7 (SD 2.6) mg kg-1. The magnetic coil was placed over the MEP scalp stimulation region and evoked electromyographic responses were recorded from the contralateral abductor pollicis brevis. After an initial dose of thiopentone, reproducible MEP responses were recorded in all patients, but amplitudes were reduced to 42.8% of baseline values. Further administration of repeated doses of thiopentone produced a dose-dependent decrease in success rate of MEP recordings and a significant reduction in MEP amplitude (P < 0.01). Latency did not change significantly, although there was a tendency to increase. During burst suppression on the EEG, MEP was not recorded successfully in all patients. We conclude that MEP recording during the administration of thiopentone is feasible only at a minimum dose, with a marked reduction in MEP amplitude.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Effect of Thiopentone on Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation in Humans

Kawaguchi

Sakamoto

Shimizu

et al. 1993

British Journal of Anaesthesia

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“…MEPs elicited by direct spinal cord stimulation are more reliable for monitoring purposes than t,mMEPs, which are markedly suppressed by anesthetic agents (16,18,20,49), and often difficult to record from extremity muscles in the presence of nitrous oxide-narcotic anesthesia (50). We were able to record MEPs elicited by spinal stimulation in 18 of 19 patients, despite the use of potent anesthetic agents in 15 of the study patients.…”

Section: Discussionmentioning

confidence: 99%

Monitoring of Intraoperative Motor-Evoked Potentials Under Conditions of Controlled Neuromuscular Blockade

Adams

Emerson

Heyer

et al. 1993

Anesthesia & Analgesia

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Motor-evoked potentials were recorded after electrical spinal cord stimulation in 19 patients undergoing neurosurgical or orthopedic procedures. Anesthesia was maintained with nitrous oxide, opioids, and inhaled anesthetics. Vecuronium was infused sufficient to eliminate 90% of twitch tension. The spinal cord was stimulated using either epidural or subarachnoid electrodes. Compound muscle action potentials were recorded from quadriceps and tibialis anterior muscles. Well-formed, stable motor-evoked potentials were recorded in all but one patient, in whom a preexisting myelopathy was felt to preclude recording. Intraoperative deterioration of motor-evoked potentials occurred in one patient who had a postoperative neurologic deficit. This study demonstrates the feasibility and utility of intraoperative motor tract monitoring using direct spinal cord stimulation. Controlled neuromuscular blockade permits recording of compound muscle action potentials while eliminating patient motor activity that could interfere with surgery.

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Myogenic Response Distortion of Neurogenic Motor Evoked Potential Morphology

Schwentker

Russell²,

Rodichok³

et al. 1995

Anesthesiology

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Effects of Four Intravenous Anesthetic Agents on Motor Evoked Potentials Elicited by Magnetic Transcranial Stimulation

Cited by 4 publications

References 0 publications

Effect of Thiopentone on Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation in Humans

Effect of Thiopentone on Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation in Humans

Monitoring of Intraoperative Motor-Evoked Potentials Under Conditions of Controlled Neuromuscular Blockade

Myogenic Response Distortion of Neurogenic Motor Evoked Potential Morphology

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