Effects of food restriction and/or aerobic exercise on the GLUT4 in type 2 diabetic male rats

Dastbarhagh, Hossien; Kargarfard, Mehdi; Abedi, Heidarali; Bambaeichi, Effat; Nazarali, Parvaneh

doi:10.4103/ijpvm.ijpvm_383_17

Cited by 5 publications

(7 citation statements)

References 51 publications

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“…The repeated, transient increases in GLUT transcription during an acute exercise bout lead to a gradual increase in GLUT4 protein after short-term exercise training [23]. Increased expression and protein content of GLUT4 have been described in response to training in T2DM [28,45,46]. In addition to the increase in GLUT4 expression and protein levels, the increases in muscle glycogen synthase, glycogen content, and hexokinase II all contribute to increased insulin sensitivity in response to training [47].…”

Section: The Long-term Effects Of Regular Exercise On Glycemic Control and Overall Health In Insulin Resistance Statesmentioning

confidence: 99%

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

et al. 2021

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Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Regular exercise is important for a healthy pregnancy and can lower the risk of developing GDM. For women with GDM, exercise is safe and can affect the pregnancy outcomes beneficially. A single exercise bout increases skeletal muscle glucose uptake, minimizing hyperglycemia. Regular exercise training promotes mitochondrial biogenesis, improves oxidative capacity, enhances insulin sensitivity and vascular function, and reduces systemic inflammation. Exercise may also aid in lowering the insulin dose in insulin-treated pregnant women. Despite these benefits, women with GDM are usually inactive or have poor participation in exercise training. Attractive individualized exercise programs that will increase adherence and result in optimal maternal and offspring benefits are needed. However, as women with GDM have a unique physiology, more attention is required during exercise prescription. This review (i) summarizes the cardiovascular and metabolic adaptations due to pregnancy and outlines the mechanisms through which exercise can improve glycemic control and overall health in insulin resistance states, (ii) presents the pathophysiological alterations induced by GDM that affect exercise responses, and (iii) highlights cardinal points of an exercise program for women with GDM.

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Section: The Long-term Effects Of Regular Exercise On Glycemic Control and Overall Health In Insulin Resistance Statesmentioning

confidence: 99%

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

et al. 2021

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“…In a study on Nigerian females Akor-Dewu et al (2012) [2] shown that RBC count varies between 4.23 millions/cu.mm and 4.33 millions/cu.mm in two differently polluted zones. Kargarfard et al (2011) [14] found a significant decrease in RBC count after exercising in polluted air. Das and Chatterjee (2015b) [7] found significant reduction in RBC count of school going boys in high polluted zone.…”

Section: Discussionmentioning

confidence: 97%

“…Numerous studies have reported short term effects of air pollution on increasing the risk of cardiorespiratory mortality and morbidity (Dockery et al, 1993;Oliveira et al, 2006) [9,20] . The extent to which an individual is affected by air pollution generally depends on the total exposure to the damaging pollutants, which is usually determined by the duration of exposure and the concentration of the chemicals (Kargarfard et al, 2011) [14] . Concern has been increased about problems associated with exercising in polluted air.…”

Section: Introductionmentioning

confidence: 99%

A comparative study on hematological profile of female athletes of two different air polluted zones of West Bengal

Mishra¹,

Ghosh²,

Banerjee³

2021

Int. J. Physiol. Nutr. Phys. Educ.

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Air pollution has become one of the health hazards of today's world. It is now well known fact the exercises in the form of sports, aerobics or workouts, if performed regularly have a positive impact on various system of the body. But during exercising one should avoid areas with high pollutant concentrations. The study was carried out to observe whether environmental air pollution has any effect on hematological parameters of female athletes of two different polluted zones of west Bengal. Two different zones (Cooch Behar -A B N Seal College, Howrah -Betore) with their respective climate condition of West Bengal, India were selected for the present study. The air quality of these different zones was collected from WBPCB for comparative study of air pollution from January 2017 to February 2017. The total number of 20 female athletes aged 18-25 years undergoing regular training program for a minimum period of 3 years and having participation in national /state/district level sports competitions and residents of that particular area for the past 5 years or more were enrolled as subjects of this study. They were subdivided into two groups according to their residence of particular zone. Selected physical profile, hematological profile and air pollutants were measured. There was no significant difference between female athletes of Cooch Behar and Howrah zones in respect of height, weight and BSA and BMI. Hb concentration, RBC count, PCV%, MCH and MCHC were significantly higher (p<0.01) in Cooch Behar female athletes than Howrah female athletes. WBC (p<0.01) and platelet count (p<0.05) were significantly higher in Howrah female athletes than Cooch Behar female athletes. No significant differences were obtained in MCV although values were higher in Cooch Behar athletes. Values of PM10 of Howrah zone was much more than the national ambient air quality standards. In the case of SO2 concentration in air, all these zones are below the standard level. Though the NO2 of Howrah and Cooch Behar zones are below the standard level, the Howrah zone is very near to cross the standard level.

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“…22 PRIMARY DIAGNOSES An important aspect of this investigation was the influence of cardiovascular and diabetes diagnoses. While CR is an established treatment for a host of CVD diagnoses, including MI 12 and PCI 24 , the independent relationship on BP is not well defined. Indeed, a preliminary investigation demonstrated that MI is associated with improvements in SBP (−1.4 mm Hg) 12 ; the impact of CR on BP in those with many other referring diagnoses has not been well described prior to this study.…”

Section: Insurance Providersmentioning

confidence: 99%

“…Successful control of SBP is nonetheless recognized as essential to long-term cardiovascular health in that CR participation is linked to declines in visit-to-visit SBP. 11 Based on this rationale, it is clear that exercise rehabilitation improves cardiovascular health, at least in part due to improvements in BP 2,10,12 ; however, several fundamental questions remain unresolved. For instance, (1) how much does rehabilitative exercise alter BP in the average CR patient?…”

mentioning

confidence: 99%

Cardiac Rehabilitation and Resting Blood Pressure

Quindry

McNamara²,

Oser³

et al. 2021

Journal of Cardiopulmonary Rehabilitation and Prevention

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Cardiac Rehabilitation and Blood Pressure E23C ardiovascular disease (CVD) remains a leading cause of morbidity and mortality in industrialized nations. 1 Prevention of recurrent CVD is linked to healthy lifestyles and risk factor mitigation. Notably, regular exercise prevents disease, but given the frequency of CVD diagnoses, exercise-based cardiac rehabilitation (CR) is essential for preventing disease recurrence. [2][3][4][5] The benefits of exercise extend to CVD risk factor management, including the control of blood pressure (BP), one of the most well-established benefits experienced by active individuals. 6 Hypertension contributes directly to many cardiac pathologies (eg, ischemic heart disease, heart failure), and hypertension is among the most modifiable CVD risk factors, whereas a 10-mm Hg drop in BP is associated with 50% lower rates in all-cause mortality. 7 Accordingly, recent Global Burden of Disease Study findings demonstrate that elevated systolic blood pressure (SBP) is among the most important contributing factors to all-cause disability. 8 Given need to improve BP management in at-risk persons, the American College of Cardiology (ACC)/American Heart Association (AHA) released revised hypertension guidelines in 2017, lowering diagnostic hypertension thresholds from 140/90 mm Hg to 130/80 mm Hg. 9 The revised guidelines reclassify the pernicious effects of hypertension by delineating pre-hypertension from stage 1 and stage 2 hypertension according to more rigorous standards, lowered in 10 mm Hg increments.Accordingly, lowering BP through comprehensive CR approaches is among the most impactful first-line treatments 10 ; however, the impact of the new BP guidelines is incomplete. Preliminary findings from a retrospective study indicated that CR reduces all-cause mortality in the approximately 6 yr of follow-up investigation, but the contribution of rehabilitative exercise to risk factor modifications, including BP, was not delineated. Successful control of SBP is nonetheless recognized as essential to long-term cardiovascular health in that CR participation is linked to declines in visit-to-visit SBP. 11 Based on this rationale, it is clear that exercise rehabilitation improves cardiovascular health, at least in part due to improvements in BP 2,10,12 ; however, several fundamental questions remain unresolved. For instance, (1) how much does rehabilitative exercise alter BP in the average CR patient? (2) Since phase II CR visits typically range between 12 and 36 visits, is there a dose response effect on BP? In addition, (3) do demographic factors (sex, race, etc), referring diagnoses, or the influence of the insurance provider alter BP? Finally, (4) it is unknown whether institution of the new ACC/AHA guidelines 12 has impacted BP in patients referred to CR. According to this rationale, we sought to answer these questions about the influence of CR on BP. METHODS CR REGISTRY AND PATIENT DATA COLLECTIONThese data were collected from the Montana Outcomes Project, a data registry developed and coordi...

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Effects of food restriction and/or aerobic exercise on the GLUT4 in type 2 diabetic male rats

Cited by 5 publications

References 51 publications

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

A comparative study on hematological profile of female athletes of two different air polluted zones of West Bengal

Cardiac Rehabilitation and Resting Blood Pressure

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