Effects of Five Products on Gut Microbiota and Short-Chain Fatty Acids of Obese Rats

Abstract

24 The effects of banana powder(BP), konjac powder(KP), resistant dextrin(RD), corn 25 starch(CS) and L-carnitine(LC) on gut microbiota and metabolites (SCFA) were 26 evaluated in order to provide basic data for the development of weight-loss functional 27 food. The gut microbiota profile using 16S V4 rDNA high-throughput sequencing 28 technique suggested that the rats of RD, BP and CS group developed an increased 29 richness and diversity in the gut bacterial community, while the abundance of the KP 30 and LC group was not enhanced obviously. Verrucomicrobiaceae, Coprococcus-2 31 and Lachnospiraceae were the main bacterial genera in the CS, BP and RD group 32 respectively, indicating their potential use as prebiotics. On the other hand, rats fed 33 with BP, KP, CS and RD contributed higher total SCFA than those feeding with LC 34 diet. Thus, RD, BP, CS, KP could moduate gut microbiota and increase the SCFA 35 concentration, while the effect of LC are not apparent. 36 Keywords 37 five products, gut microbiota, short chain fatty acids. 38 39 40 41 42 43 44 3 45

Nutraceutical Properties of Unripe Banana Flour Resistant Starch: A Review

“…Unripe banana flour was also associated with the proliferation of Verrucomicrobiaceae and Coprococcus-2 as well as Lachnospiraceae. [57] The changes in microbial populations associated with obesity include decreased diversity in microbiota, reduction in Escherichia coli and Bifidobacterium, and increase in Methanobacteria smithii, Lactobacillus, and the F/B ratio. [58] These changes are associated with increased dietary energy sequestration by bacteria, increased transmembrane transport, [59] and increased cellular deposition of triglycerides due to decreased activity of the fasting-induced adipose factor [41] and the breakdown of otherwise unavailable carbohydrates.…”