Effects of Fermented Milk Containing Herb Extract from Acanthopanax divaricatus var. albeofructus and Codonopsis Ianceolata on the Immune Status of Mouse

Lim, Sang-Dong; Seong, Ki-Seung; Kim, Kee-Sung; Han, Dong-Un

doi:10.5851/kosfa.2007.27.1.95

Cited by 7 publications

(3 citation statements)

References 9 publications

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“…Recently, several studies on immunopotentiating activity from plant source were occurred. Lim et al ( 2007 ) reported that water extracts of Acanthopanax divaricatus var. alveofructus and Codonopsis lanceolata showed a significant immunomodulatory activity such as production of IgG antibodies.…”

Section: Resultsmentioning

confidence: 99%

Effect of mucilage from yam on activation of lymphocytic immune cells

2007

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The immunostimulating activities of mucilage fraction from yam were investigated. The proliferation of BSA-primed lymph node cells was enhanced between 4.1- to 10.9-fold compare to control, when cultured with 1 to 25 µg/mL of yam-mucilage fraction. It showed strong immunopotentiating activity than ginseng extract and as remarkable as Bifidobacterium adolescentis M101-4 known as a positive immunostimulator. Mitogenicity to lymph node cells was fully induced by concanavalin A and lipopolysaccharide. The proliferation of splenocytes and Peyer's patch cells was enhanced between 5.0- to 14.1-fold and 2.4- to 6.4-fold, respectively, when cultured with 1 to 25 µg/mL of yam-mucilage fraction. It enhanced the production of cytokines such as tumor necrosis factor-α and IL-6 in the culture of RAW 264.7 macrophage cells. In the culture of lipopolysaccharide-stimulated RAW 264.7 cells, production of cytokines was as similar as compared to controls. In unstimulated RAW 264.7 cells, both tumor necrosis factor-α and IL-6 production were enhanced between 15.6- to 60.1-fold and 2.3- to 9.1-fold, respectively. Mucilage fraction from yam is expected to be a safe immunopotentiator to maintain the host immunity and develop a physiologically functional food.

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Section: Resultsmentioning

confidence: 99%

Effect of mucilage from yam on activation of lymphocytic immune cells

2007

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“…또한 더덕의 주성분은 saponin, inulin과 flavonoid 등으로 알려져 있고 [5], 더덕 에탄올 추출물과 더덕의 부 위별 세표벽 물질의 항산화 효과 및 면역력 증가 효과가 있다고 보고되었다 [6][7][8][9][10][11].…”

Section: 서론 더덕(Codonopsis Lanceolata B)은 도라지과(Compa-unclassified

The Study on Skin Safety and Efficacy of Codonopsis Lanceolata Root Fermentation Extract

Shim¹,

Chun²

2012

Journal of the Korea Academia-Industrial cooperation Society

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Codonopsis lanceolata belongs to the Campanulaceae family, which is a perennial herb. It is widely used as an antitussive agent and an expectorant in oriental medicine. Codonopsis lanceolata contains large amounts of polysaccharide and phenolic compounds and is known to have anti-oxidative effect and improve immunity. We evaluated the efficacy and the skin safety and stability of cosmetic that is applied Codonopsis lanceolata extract fermented by lactic acid bacteria. As result, formulation of Codonopsis lanceolata extract improved the human skin moisturizing effect, increased TEWL 196%, skin hydration 15%, and the sebum rate 131%.

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“…We are faced with a variety of processed foods and a number of medications, which can cause health problems. Research has shown that various natural products act as effective agents for enhancing the immune system, reducing reactive oxygen species, accelerating alcohol metabolism, and functioning as an alternative or functional food (1)(2)(3).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Ground Cherry Extract on the Activity of Hepatic Aniline Hydroxylase in Mice

S¹,

Lee²

2008

JFN

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To evaluate the effect of ground cherry extract on the activity of aniline hydroxylase, we gave ground cherry extract in doses of 100, 200 or 400 mg/kg i.p to mice for 1, 2 or 4 days. The aniline hydroxylase activity in the group treated with ground cherry extract increased in a dose dependant manner in all experimental groups compared with the control group, and was significantly higher in the group treated with ground cherry extract at a dose of 200 mg/kg, which also exhibited a time dependant increase over 4 days. Enzyzme kinetic analysis was performed for hepatic aniline hydroxylase activity in the group treated with 200 mg/kg for 4 days. There was no change of the Km values for aniline hydroxylase between the experimental group and the control group, but the Vmax values for aniline hydroxylase was 21% lower in the experimental group compared with the control. The experimental group also showed lower lipid peroxide and reduced glutathione content, and there were no significant difference in serum alanine aminotransferase activity between the experimental group and the control. Aniline was injected into both the experimental group mice treated with ground cherry extract at a dose of 200 mg/kg for 4 days and the control group, and then the level of blood aniline was assayed at 1hr. The level of blood aniline was lower in the experimental than the control group. This study suggests that ground cherry extract induces hepatic aniline hydroxylase activity and might accelerate the scavenging system of reactive oxygen species. It is likely that ground cherry extract influences the metabolism of xenobiotics by activating AH activity substituted for CYP2E1.

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Effects of Fermented Milk Containing Herb Extract from Acanthopanax divaricatus var. albeofructus and Codonopsis Ianceolata on the Immune Status of Mouse

Cited by 7 publications

References 9 publications

Effect of mucilage from yam on activation of lymphocytic immune cells

Effect of mucilage from yam on activation of lymphocytic immune cells

The Study on Skin Safety and Efficacy of Codonopsis Lanceolata Root Fermentation Extract

The Effect of Ground Cherry Extract on the Activity of Hepatic Aniline Hydroxylase in Mice

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