Effects of feminine cleanser Inclear on sperm motility: A prospective study

Abstract

ObjectiveThe objective of this study is to estimate the effects of Inclear, a feminine cleanser, on sperm motility.MethodsSemen samples were obtained from infertile male patients. Following liquefaction, the raw semen samples were diluted with Ham's F-10 nutrient mixture medium containing 0.4% human serum albumin solution at a ratio of 1:3. The semen samples were subsequently centrifuged to separate the seminal plasma from the serum. The supernatant was discarded, and the pellet was resuspended. The sample was again centrifuged to remove cell debris, and the supernatant was removed. The final pellet was gently loosened by resuspension and incubated in medium alone as a control, and in a 10% solution of the medium plus Inclear. A sampling time of 30 minutes was selected on the basis of sperm transport studies. Sperm motility was evaluated with computer-assisted sperm analysis.ResultsA total of 20 samples were analyzed. The mean age of patients was 34.40±2.96 years. There was no difference in sperm concentration and motility in the two samples at 0 minute and 30 minutes of incubation. In both semen samples, the sperm concentration and motility decreased after an incubation period of 30 minutes. However, there was no statistical difference between the samples. Sperm concentration and motility were not significantly different between the control and Inclear samples after 0 minute and 30 minutes of incubation.ConclusionInclear has no negative effects on sperm motility. This product can be recommended to pregnancy planners for vaginal hygiene and as a vaginal lubricant.

Carrageenan: Future Potential Ingredient of Lubricant and Feminine Hygiene Product with Possible Protection Effects against HPV Infection

“…84 Feminine cleanser has no negative effects on sperm motility. 85 Carrageenan has the potential for application in feminine cleanser products due to its gelling and biological properties . The use of carrageenan in feminine cleanser not only maintains vaginal health against bacterial infections but also prevents HPV infection and inflammation of vaginal areas.…”