Effects of Fatty Acids on Hematological Neoplasms: A Mini Review

Giannattasio, Silvia; Dri, Maria; Merra, Giuseppe; Caparello, Giovanna; Rampello, Tiziana; Renzo, Laura Di

doi:10.1080/01635581.2021.1960389

Cited by 2 publications

(2 citation statements)

References 57 publications

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“…Polyunsaturated fatty acids (PUFAs) are a group of compounds containing at least 18 carbon atoms and two double bonds in their chemical molecular structure. Examples of such compounds are α-linolenic acid, 18:3 (ω-3), arachidonic acid, 20:4 (ω-6), docosahexaenoic acid, 22:6 (ω-3) (DHA), and eicosapentaenoic acid 20:5 (ω-3) (EPA) [ 84 , 85 , 86 , 87 ]. The omega-6 PUFAs exhibit pro-inflammatory effects by stimulating the production of specific cytokines, while the omega-3 PUFAs are widely regarded as those showing anti-inflammatory and immunomodulatory properties [ 21 ].…”

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

“…The omega-6 PUFAs exhibit pro-inflammatory effects by stimulating the production of specific cytokines, while the omega-3 PUFAs are widely regarded as those showing anti-inflammatory and immunomodulatory properties [ 21 ]. The latter belong to a group of macromolecules with well-established evidence of positive impact when used in patients with haematological proliferative diseases, including in patients post-HSCT [ 84 , 85 , 86 , 87 ].…”

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

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The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

et al. 2023

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Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and post-transplant periods. Patients may require nutritional treatment by the enteral or parenteral route. The quantitative and qualitative composition of meals may change. Vitamin requirements, including vitamin D and vitamin C, might also be different. An adequately composed diet, adapted to the needs of the patient, may influence the occurrence of complications such as graft-versus-host disease (GvHD), gastrointestinal disorders, infections, and reduced survival time. Haematological diseases as well as transplantation can negatively affect the intestinal flora, with negative consequences in the form of mucosal inflammation and disorders of a functional nature. Currently, aspects related to nutrition are crucial in the care of patients after HSCT, and numerous studies, including randomized trials on these aspects, are being conducted. This study serves the critical analysis of current scientific evidence regarding nutritional support for patients after HSCT.

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Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

et al. 2023

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Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm

Singh,

Peshin,

Larsen

et al. 2024

Curr Oncol Rep

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Purpose of Review Myeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical, psychological, and social well-being. While pharmacological interventions offer some disease and symptom control, they often have unfavorable side effects. This review explores the potential of Integrative Oncology (IO) therapies in managing MPNs and their associated symptoms. Recent Findings IO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive care therapies. Several small studies suggest the benefit of an IO approach in MPN patients. These benefits are postulated to be modulated through enhanced physical capacity, reduced disease-related inflammation, subconscious mind training, and gut microbiome modulation. Summary By combining IO with evidence-based pharmacological treatments, the potential exists to enhance the quality of life and clinical outcomes for individuals with MPNs. Future research should prioritize well-powered studies, including diverse demographics and symptom profiles, with appropriate study duration, to draw definite conclusions regarding the observed effects.

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Effects of Fatty Acids on Hematological Neoplasms: A Mini Review

Cited by 2 publications

References 57 publications

The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm

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