Effects of extracted polysaccharides from a Chlorella vulgaris biomass on expression of interferon-γ and interleukin-2 in chicken peripheral blood mononuclear cells

Effect of Feeding 0.8% Dried Powdered Chlorella vulgaris Biomass on Growth Performance, Immune Response, and Intestinal Morphology during Grower Phase in Broiler Chickens

“…Researchers show that adding fermented CV [19], or dried or fresh CV powder [4,18], at a dosage of 1-2% into broiler diets improves growth performance, modulates immune response, and affects the intestinal tissue morphology in broilers. These studies [18,19] confirm the use of CV biomass at low dosages in broiler diets, which confers the functional properties attributed to CV products in other studies [2,5,[13][14][15][16][17]20]. It is economically valuable for farmers to use CV biomass at even lower dosages, if the functional properties are conserved.…”

“…However, the suppressed production of IL-13 is in agreement with other studies conducted on mice [35] and humans [36] treated with CV products. The reason for of the reduction of Hap and Il-13 response in serum could be a direct effect of various bioactive components in microalgae on immune cells, such as xantophylls [37,38], phytosterols [38,39], PUFA [40], peptides [41], and polysaccharides [20].…”

Effects of Chinese yam polysaccharides on the immune function and serum biochemical indexes of broilers

“…Li et al ( 20 ) observed that 50 mg/mL supplementation of Taishan Pinus massoniana pollen polysaccharides can significantly increase the IL-2 level of immunosuppressed chickens, proving that these polysaccharides could promote the immune regulation ability of cytokines. Mirzaie et al ( 33 ) showed that the supplementation of Chlorella Vulgaris polysaccharides could induce peripheral blood mononuclear cells and promote IL-2 expression in broilers. In the present study, 0.50 g/kg CYP supplementation increased the serum concentrations of TNF-α, IL-2, IL-4 and IL-6.…”