Effects of extracellular vesicles from adipose‐derived stem cells on human keloid fibroblasts via the SOCS1/JAK2/STAT3 pathway
Hongru Ruan,
Jie Wang,
Hui Shi
et al.
Abstract:BackgroundKeloid represents a benign skin tumor with many cancer‐like features. Extracellular vesicles (EVs) derived from human adipose‐derived stem cells (hADSCs) play a role in cell migration of multiple diseases.AimsThis study aimed to investigate the impact of hADSC‐EVs on human keloid fibroblasts (HKFs).MethodshADSCs were cultured to the 3rd generation, and subsequently assessed for their osteogenic, adipogenic, and chondrogenic differentiative abilities using flow cytometry, alizarin red, oil red O, and … Show more
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