Effects of extra irradiation on surface and bulk properties of <scp>PMPC</scp>‐grafted cross‐linked polyethylene

Yamane, Satoshi; Kyomoto, Masayuki; Moro, Toru; Watanabe, Kenichi; Hashimoto, Masami; Takatori, Yoshio; Tanaka, Sakae; Ishihara, Kazuhíko

doi:10.1002/jbm.a.35538

Cited by 4 publications

(5 citation statements)

References 40 publications

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“…[ 76 ] PMPC-grafted CLPE receiving gamma-ray irradiation showed higher ultimate tensile strength and elongation than those receiving non-extra or plasma irradiation. [ 72 ] Conversely, failure of PMPC-grafted CLPE with gamma-ray irradiation was significantly lower than those receiving non-extra or plasma irradiation. Moreover, plasma-irradiated PMPC-grafted CLPE showed significantly higher impact strength than those in the gamma-irradiated sample.…”

Section: Surface Modification Techniques and Their Recent Developmentmentioning

confidence: 99%

“…Though PMPC-grafted CLPE liner treated with extra irradiation of plasma irradiation or gamma-ray exhibited no significant differences in wettability and wear resistance properties, the plasma irradiation showed improved oxidation resistance as compared to that treated with gamma-ray irradiation after accelerated ageing. [ 72 ]…”

Section: Surface Modification Techniques and Their Recent Developmentmentioning

confidence: 99%

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Status of surface modification techniques for artificial hip implants

Ghosh

Abanteriba

2016

Science and Technology of Advanced Materials

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Surface modification techniques have been developed significantly in the last couple of decades for enhanced tribological performance of artificial hip implants. Surface modification techniques improve biological, chemical and mechanical properties of implant surfaces. Some of the most effective techniques, namely surface texturing, surface coating, and surface grafting, are applied to reduce the friction and wear of artificial implants. This article reviews the status of the developments of surface modification techniques and their effects on commonly used artificial joint implants. This study focused only on artificial hip joint prostheses research of the last 10 years. A total of 27 articles were critically reviewed and categorized according to surface modification technique. The literature reveals that modified surfaces exhibit reduced friction and enhanced wear resistance of the contact surfaces. However, the wear rates are still noticeable in case of surface texturing and surface coating. The associated vortex flow aids to release entrapped wear debris and thus increase the wear particles generation in case of textured surfaces. The earlier delamination of coating materials due to poor adhesion and graphitization transformation has limited the use of coating techniques. Moreover, the produced wear debris has adverse effects on biological fluid. Conversely, the surface grafting technique provides phospholipid like layer that exhibited lower friction and almost zero wear rates even after a longer period of friction and wear test. The findings suggest that further investigations are required to identify the role of surface grafting on film formation and heat resistance ability under physiological hip joint conditions for improved performance and longevity of hip implants.

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Section: Surface Modification Techniques and Their Recent Developmentmentioning

confidence: 99%

Section: Surface Modification Techniques and Their Recent Developmentmentioning

confidence: 99%

Status of surface modification techniques for artificial hip implants

Ghosh

Abanteriba

2016

Science and Technology of Advanced Materials

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“…No adverse effects and no revision surgery and no osteolysis were informed and observed. However, cobalt-chromium-molybdenum (Co-Cr-Mo) and cobalt-chromium (Co-Cr) alloys were used in recent studies as the head material against PMPC-grafted CLPE liner [67][68][69][70][71].…”

Section: Surface Coatingsmentioning

confidence: 99%

An Overview on the Tribological Performance of Titanium Alloys with Surface Modifications for Biomedical Applications

2019

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The need for metallic biomaterials will always remain high with their growing demand in joint replacement in the aging population. This creates need for the market and researchers to focus on the development and advancement of the biometals. Desirable characteristics such as excellent biocompatibility, high strength, comparable elastic modulus with bones, good corrosion resistance, and high wear resistance are the significant issues to address for medical implants, particularly load-bearing orthopedic implants. The widespread use of titanium alloys in biomedical implants create a big demand to identify and assess the behavior and performance of these alloys when used in the human body. Being the most commonly used metal alloy in the fabrication of medical implants, mainly because of its good biocompatibility and corrosion resistance together with its high strength to weight ratio, the tribological behavior of these alloys have always been an important subject for study. Titanium alloys with improved wear resistance will of course enhance the longevity of implants in the body. In this paper, tribological performance of titanium alloys (medical grades) is reviewed. Various methods of surface modifications employed for titanium alloys are also discussed in the context of wear behavior.

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“…Furthermore, the MPC polymer has been clinically used on the surfaces of intravascular stents, intravascular guidewires, soft contact lenses, and artificial lungs. To reduce UHMWPE wear and eliminate osteolysis, a novel UHMWPE liner with MPC grafted onto its surface (Aquala) has been developed [ 44 , 45 , 46 ]. For MPC grafting, polyethylene liners are placed in MPC solution after being coated with benzophenone as a photosensitizer, followed by photoinduced polymerization on the liner surface with an ultra-high-pressure mercury lamp [ 45 ].…”

Section: First-generation Hxlpementioning

confidence: 99%

“…Despite the favorable data collected with in vitro simulation and promising clinical reports [ 45 , 46 , 47 , 48 ], the MPC layer peeled off from the bearing surfaces of short-term-retrieved liners in several studies [ 49 , 50 ]. Additionally, MPC grafting also does not protect HXLPE against oxidation [ 49 ], and the extent of surface oxidation and the presence of different alkoxyl CO• radical species have been previously revealed [ 50 ].…”

Section: First-generation Hxlpementioning

confidence: 99%

Ultra-High-Molecular-Weight Polyethylene in Hip and Knee Arthroplasties

et al. 2023

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Ultra-high-molecular-weight polyethylene (UHMWPE) wear and particle-induced osteolysis contribute to the failure of total hip arthroplasty (THA) and total knee arthroplasty (TKA). Highly crosslinked polyethylene (HXLPE) was developed in the late 1990s to reduce wear and has shown lower wear rates and loosening than conventional UHMWPE in THA. The irradiation dose for crosslinking is up to 100 kGy. However, during crosslinking, free radical formation induces oxidation. Using HXLPE in THA, the cumulative revision rate was determined to be significantly lower (6.2%) than that with conventional UHMWPE (11.7%) at a mean follow-up of 16 years, according to the Australian Orthopaedic Association National Joint Replacement Registry. However, HXLPE does not confer to TKA the same advantages it confers to THA. Several alternatives have been developed to prevent the release of free radicals and improve polymer mechanical properties, such as thermal treatment, phospholipid polymer 2-methacryloyloxyethyl phosphorylcholine grafting, remelting, and vitamin E addition. Among these options, vitamin E addition has reported good clinical results and wear resistance similar to that of HXLPE without vitamin E, as shown by short-term clinical studies of THA and TKA. This review aims to provide a comprehensive overview of the development and performance of UHMWPE in THA and TKA.

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Effects of extra irradiation on surface and bulk properties of PMPC‐grafted cross‐linked polyethylene

Cited by 4 publications

References 40 publications

Status of surface modification techniques for artificial hip implants

Status of surface modification techniques for artificial hip implants

An Overview on the Tribological Performance of Titanium Alloys with Surface Modifications for Biomedical Applications

Ultra-High-Molecular-Weight Polyethylene in Hip and Knee Arthroplasties

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