Effects of exercise training in heart failure with preserved ejection fraction: an updated systematic literature review

Leggio, Massimo; Fusco, Augusto; Loreti, Claudia; Limongelli, G; Bendini, Maria Grazia; Mazza, Andrea; Coraci, Daniele; Padua, Luca

doi:10.1007/s10741-019-09841-x

Cited by 51 publications

(42 citation statements)

References 42 publications

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“…Home-based individual cardiac rehabilitation (alone or in combination with centre-based cardiac rehabilitation) 73 is also feasible using technology-based telemedicine programmes, 74 in combination with home visits and telephone support when appropriate. 75 Further research is required to investigate the impact of exercise-based cardiac rehabilitation on older and/or frail/cachectic patients and those with CHF with preserved ejection fraction 76 or nonischaemic CHF. 77…”

Section: Chfmentioning

confidence: 99%

Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology

Ambrosetti

Abreu

Corrà

et al. 2020

European Journal of Preventive Cardiology

530

604

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Secondary prevention through comprehensive cardiac rehabilitation has been recognized as the most cost-effective intervention to ensure favourable outcomes across a wide spectrum of cardiovascular disease, reducing cardiovascular mortality, morbidity and disability, and to increase quality of life. The delivery of a comprehensive and ‘modern’ cardiac rehabilitation programme is mandatory both in the residential and the out-patient setting to ensure expected outcomes. The present position paper aims to update the practical recommendations on the core components and goals of cardiac rehabilitation intervention in different cardiovascular conditions, in order to assist the whole cardiac rehabilitation staff in the design and development of the programmes, and to support healthcare providers, insurers, policy makers and patients in the recognition of the positive nature of cardiac rehabilitation. Starting from the previous position paper published in 2010, this updated document maintains a disease-oriented approach, presenting both well-established and more controversial aspects. Particularly for implementation of the exercise programme, advances in different training modalities were added and new challenging populations were considered. A general table applicable to all cardiovascular conditions and specific tables for each clinical condition have been created for routine practice.

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Section: Chfmentioning

confidence: 99%

Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology

Ambrosetti

Abreu

Corrà

et al. 2020

European Journal of Preventive Cardiology

530

604

View full text Add to dashboard Cite

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“…Impact of ET on diastolic function parameters: The comparison between the 2 groups showed statistically significant difference in the E wave velocity, DD grade, EDT, PASP, septal e`, lateral e`, E/e` and LAVI denoting more improvement with CR while no significant difference between the 2 groups was found in the A wave velocity, E/A ratio, EF, LVH degree, LAD and IVRT. Tables 2 and 3 (27) On reviewing the previous trials that have studied the impact of ET on HFpEF, we found large variation in the designs of those studies regarding different aspects. The duration of the ET protocol varied from 12 to 16 weeks in most studies (27) although some studies used shorter protocols as the 4-week ET program in the study done by Angadi et al (28) and other longer protocols such as the 20week protocol which was reported by Kitzman et al 2016.…”

Section: Resultsmentioning

confidence: 99%

“…Tables 2 and 3 (27) On reviewing the previous trials that have studied the impact of ET on HFpEF, we found large variation in the designs of those studies regarding different aspects. The duration of the ET protocol varied from 12 to 16 weeks in most studies (27) although some studies used shorter protocols as the 4-week ET program in the study done by Angadi et al (28) and other longer protocols such as the 20week protocol which was reported by Kitzman et al 2016. (29) Also the ET was done in variable settings whether home based outpatient setting or a supervised program done in rehabilitation centers.…”

Section: Resultsmentioning

confidence: 99%

“…The mode of ET JMRI, 2021, Vol.42 No.1: (1)(2)(3)(4)(5)(6)(7)(8) also varied where some studies used a combination of endurance and resistance training, others adopted walking on a treadmill and other studies used the bicycle ergometer. (27) In our study, we followed a 12-week ET program using walking on a treadmill as the core of our CR program. We do believe that this design was appropriate for keeping the compliance of the patients with no patients lost in the follow up in our study.…”

Section: Resultsmentioning

confidence: 99%

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Impact of Cardiac Rehabilitation on Patients With Heart Failure With Preserved Ejection Fraction

Hassanein

Ayad

Amrawy

et al. 2021

Journal of the Medical Research Institute

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Background: Heart failure with preserved ejection fraction (HFpEF) represents more than one half of the heart failure (HF) cases worldwide with increased morbidity and mortality. No proven medical treatment till now has shown mortality benefit in HFpEF. This study aims to elucidate the benefit of cardiac rehabilitation (CR) in HFpEF. Methods: 60 patients with HFpEF included in 2 groups with 1:1 randomization. The first group (the rehabilitation group) received usual medical care plus 2-3 rehabilitation sessions per week for 12 weeks using moderate intensity exercise with 40-75% of heart rate reserve on treadmill (up to 60 minutes according to the functional capacity). The second group (the control group) received only usual medical care. Comparison between the 2 groups using the percentage of improvement in echocardiographic diastolic function parameters, Minnesota living with heart failure questionnaire (MLWHFQ) and 6-minute walk test at baseline and after 12 weeks. Results: we found statistically significant difference between the two groups in favor of the rehabilitation group in the following parameters: a. MLWHFQ (total score mean percentage of reduction) 305.60 ± 158.44 versus (vs.) 69.44 ± 17.71 (p<0.001). b. E/e` mean percentage of reduction 65.96 ± 34.55 vs. 18.23 ± 13.98 (p<0.001). c. Left atrial volume index (LAVI) mean percentage of reduction 27.86 ± 13.27 vs. 8.03 ± 4.40 (p<0.001). d. Pulmonary artery systolic pressure mean percentage of reduction was 33.85 ± 14.68 vs. 22.97 ± 16.54 (p=0.02). e. 6-minute walk test 111.79 ± 40.97 vs. 46.33 ± 11.58 (p<0.001). f. Body mass index percentage of reduction 10.17 ± 3.64 vs. 2.80 ± 1.60 p<0.001. g. Percentage of patients with down-grading of the grade of diastolic dysfunction 10 patients (33.3%) vs. 3 patients (10%) (P=0.028). h. No significant difference in left ventricular ejection fraction or other parameters as E/A ratio, left atrial dimension , isovolumetric relaxation time, degree of left ventricular hypertrophy. Conclusion: Cardiac rehabilitation not only added significant functional improvement in the quality of life and functional capacity but also a significant structural improvement by improving the core items of diastolic function. In the Light of this study, we recommend exercise training based cardiac rehabilitation in HFpEF management

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“…Zuletzt soll auf Patienten mit diastolischer Herzinsuffizienz ("preserved ejection fraction", HFpEF) hingewiesen werden. Eine aktuelle Zusammenstellung von 9 Studien (2000-2018) zeigte eindeutig einen positiven Effekt auf ▪ die maximale Leistungsfähigkeit, ▪ den 6-Minuten-Gehtest und ▪ die aerobe ventilatorische Schwelle [12].…”

Section: Diastolische Herzinsuffizienzunclassified

Sport und Bewegung in Prävention und Therapie kardiovaskulärer Erkrankungen

Weisser¹

2021

Dtsch Med Wochenschr

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Effects of exercise training in heart failure with preserved ejection fraction: an updated systematic literature review

Cited by 51 publications

References 42 publications

Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology

Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology

Impact of Cardiac Rehabilitation on Patients With Heart Failure With Preserved Ejection Fraction

Sport und Bewegung in Prävention und Therapie kardiovaskulärer Erkrankungen

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