Effects of exercise on vaccine-induced immune responses

Edwards, Kate M.; Booy, Robert

doi:10.4161/hv.23365

Cited by 26 publications

(25 citation statements)

References 19 publications

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“…Instituto Butantan supplied the study’s product and had no other role in the trial. Haas et al, 2021 , Hall et al, 2021 , Vasileiou et al, 2021 , Geisen et al, 2021 , Boyarsky et al, 2021 , Boyarsky et al, 2021 , Simon et al, 2021 , Boyarsky et al, 2021 , Medeiros-Ribeiro, 2021 , Simpson et al, 2015 , Chastin et al, 2021 , Bull et al, 2020 , Ekelund et al, 2016 , Joffe et al, 2012 , Robins, 2001 , Nicholson et al, 2003 , Pascoe et al, 2014 , Hilleman, 2000 , Villari et al, 2004 , Polack et al, 2020 , World Health Organization, 2021 , Grant et al, 2008 , Keylock et al, 2007 , Kohut et al, 2002 , Kohut et al, 2004 , Schuler et al, 2003 , Smith et al, 2004 , Woods et al, 2009 , Yang et al, 2007 , Stamatakis et al, 2019 , Edwards and Booy, 2013 , Edwards et al, 2012 , Edwards et al, 2007 , Viswanathan et al, 2005 , Siu et al, 2012 , Tison et al, 2020 , Wilder-Smith and Mulholland, 2021 , Jara et al, 2021 , Khoury et al, 2021 , World Health Organization (WHO) 2021 , Sallis et al, April 2021 .…”

Section: Funding Sourcementioning

confidence: 99%

Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseases

Gualano

Lemes

Silva

et al. 2022

Brain, Behavior, and Immunity

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Section: Funding Sourcementioning

confidence: 99%

Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseases

Gualano

Lemes

Silva

et al. 2022

Brain, Behavior, and Immunity

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“…Vaccination with inactivated--virus vaccines has been reported to inflict minimal disruptions to the training and competition regimes of elite athletes (39). Reports of populations of actively training elite athletes which demonstrate enhanced immunity coupled with a negligible prevalence of vaccine--induced training disruptions, reinforces the significant body of evidence which extols the effectiveness of intense physical activity as a functional adjuvant to vaccination with inactivated--virus vaccines (40,41,42,43).…”

Section: Emergent Properties Arising From the Intersection Of Sars-cov-2 Spike Protein Toxicity Sars-cov-2 Vaccination Technology And Thementioning

confidence: 96%

Vaccination of elite athletes against SARS-CoV-2 and broader implications for public health policy

Sheehan¹

2022

Preprint

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SARS-CoV-2, a human β-coronavirus implicated as thecausative agent in the COVID-19 pandemic, has been the subject of the most globally intensive vaccine development effort inrecorded history. The spectrum of SARS-CoV-2 vaccine candidates, deployedglobally, demonstrates an expansive diversity in regardsto design philosophies and immunological mechanisms of action. In the context of an aging, physically deconditioned, and overweight global population, which finds itself heavily burdened by a high prevalence of non-communicable chronic disease; elite strength, power and endurance athletes represent a minority population comprised of extreme physiological outliers. This report explores the molecular toxicity and pathophysiology of the SARS-CoV-2 spike protein, the design and immunological strategies embodied by the spectrum of SARS-CoV-2 vaccine candidates, and the intersection of these phenomena with the demographic, lifestyle and physiological characteristics of elite athletes; so as to inform vaccination strategies against SARS-CoV-2 which most protect this outlying minority population.

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“…Our data will be compared to local and systemic reactions (reactogenicity) of the COVID-19 vaccines reported by participants of clinical trials [7][8][9][10][11][12][13][14] and participants of vsafe or other prospective studies [15,16] 0 to 7 days after the injection. We will take into account confounding factors [17][18][19][20][21][22], previously proposed approaches [22][23][24] and will also review reports from social media and clinical case studies. Literature reviews of long-term and unusual side effects of COVID-19 vaccines will be performed continuously, including evaluation of dynamically evolving Adverse Events of Special Interest (AESI) and establishing background rates for these AESI [25][26][27][28][29][30][31][32][33][34][35][36].…”

Section: Potential Benefitsmentioning

confidence: 99%

Community-Based Phenotypic Study of Safety, Tolerability, Reactogenicity and Immunogenicity of Emergency-Use-Authorized Vaccines Against COVID-19 and Viral Shedding Potential of Post-Vaccination Infections: Protocol for an Ambispective study

Gabashvili¹

2021

Preprint

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The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a global pandemic that disrupted and impacted lives in unprecedented ways. Within less than a year after the beginning of the COVID-19 pandemic, vaccines developed by several research teams were emergency-use authorized and made their way to distribution sites across the US and other countries. COVID-19 vaccines were tested in clinical trials with thousands of participants before authorization, and were administered to over a billion people across the globe in the following 6 months. Post-authorization safety monitoring was performed using pre-existing systems (such as the World Health Organization's platform VigiBase or US Vaccine Adverse Event Reporting System, VAERS) and newly developed post-vaccination health checkers (such as V-safe in the US). Vaccinated individuals were also posting their experiences on multiple social media groups created on Facebook, Reddit, Telegram and other platforms, but the groups were often removed as "proliferating false claims". These forms of reporting are susceptible to biases and misclassifications and do not reach all vaccinated individuals, raising questions about risks of exacerbating health inequalities as well as security and privacy vulnerabilities. The objective of this paper is to present the protocol for a community-based participatory research approach enabling long-term monitoring of health effects, strengthening community participation via transparent messaging and support, and addressing challenges of transitioning to a new normal.

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Effects of exercise on vaccine-induced immune responses

Cited by 26 publications

References 19 publications

Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseases

Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseases

Vaccination of elite athletes against SARS-CoV-2 and broader implications for public health policy

Community-Based Phenotypic Study of Safety, Tolerability, Reactogenicity and Immunogenicity of Emergency-Use-Authorized Vaccines Against COVID-19 and Viral Shedding Potential of Post-Vaccination Infections: Protocol for an Ambispective study

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