Effects of exercise‐induced dyspnoea on the aspiration rate among patients with acute exacerbation of chronic obstructive pulmonary disease

Abstract

Purpose To use radionuclide imaging to investigate silent aspiration among patients recovering from an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We also evaluated the effects of exercise‐induced dyspnoea on silent aspiration in COPD patients. Patients and methods Recovering AECOPD patients admitted to the First Affiliated Hospital of Guangzhou Medical University between December 2013 and December 2015 were selected for the radionuclide aspiration test along with healthy volunteers of similar age. Aspiration‐negative AECOPD patients were randomized into two subgroups. Patients in group A performed symptom‐limited incremental cycle exercise test. Patients in group B were resting on the exercise bicycles. Aspiration‐negative healthy volunteers performed symptom‐limited incremental cycle exercise test (group C). Three groups performed a radionuclide aspiration test 30 min after exercise. Results The silent aspiration rates among recovering AECOPD patients and healthy volunteers were 44.19% (57/129) and 0 (0/18) (P = 0.00). The aspiration rates in groups A and B were 33.33% (10/30) and 23.33% (7/30), (P = 0.39) and groups A and C were 33.33% (10/30) and 0% (0/12), (P = 0.04). Conclusion Recovering AECOPD patients had significantly higher silent aspiration rates than healthy volunteers of similar age. The evidence is not strong enough to support the patients with exercise‐induced dyspnoea‐increased aspiration rate.

Identifying patterns of kinesiophobia trajectories among COPD patients: A longitudinal study

“…These factors include ventilation, cardiovascular, musculoskeletal, severe pain，obesity or malnutrition, mental disorders, sleep disorders, etc. Although activity restriction in COPD is influenced by multiple factors, dyspnoea associated with acute disorders of dynamic ventilatory mechanics is a major symptom of restricted exercise in most COPD patients, leading to the occurrence of kinetophobia, thus causing patients to fear lung rehabilitation training, affecting the recovery of the disease and improvement of lung function (Liu et al, 2019 ).…”

Throat microbiota drives alterations in pulmonary alveolar microbiota in patients with septic ARDS

“…Recent research has indicated that the transfer of microflora from the stomach and/or throat to the lower respiratory tract is one of the major pathogenic mechanisms in patients with severe pneumonia. Moreover, relevant literature has reported the occurrence of silent aspiration in recovered AECOPD patients, with a significantly higher incidence rate compared to age-matched healthy volunteers [ 15 ]. Additionally, literature supports the notion that microaspiration under the glottis can impact lung microflora [ 16 ].…”