Effects of Exercise Alone or in Combination with High-Protein Diet on Muscle Function, Aerobic Capacity, and Physical Function in Middle-Aged Obese Adults: A Randomized Controlled Trial

Hsu, Kuo-Jen; Chien, Kuei‐Yu; Tsai, Shiow-Chwen; Tsai, Yung-Shen; Liao, Yi Hung; Chen, J. J.; Chen, Y. R.; Chen, Chiao Nan

doi:10.1007/s12603-021-1599-1

Cited by 16 publications

(18 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies of the overweight and obese involved in exercise programs showed improvements in physical measures. Dieli-Conwright et al [ 44 ] found important improvements in estimated VO 2 max (52%) and muscular strength (>30%), as did Hsu et al [ 45 ], who recorded increases in maximal exercise capacity and maximal muscular strength. Balducci et al [ 46 , 47 ] reported positive changes in VO 2 max, upper- and lower-body strength, and flexibility.…”

Section: Discussionmentioning

confidence: 90%

Impact of BMI, Physical Activity, and Sitting Time Levels on Health-Related Outcomes in a Group of Overweight and Obese Adults with and without Type 2 Diabetes

Pippi

Cugusi

Bergamin

et al. 2022

JFMK

View full text Add to dashboard Cite

Physical activity level and sedentary behaviors affect health status in people with obesity and type 2 diabetes (DM2); their assessment is mandatory to properly prescribe exercise programs. From January 2011 to February 2014, 293 overweight/obese adults (165 women and 128 men, mean age of 51.9 ± 9.5 years and 54.6 ± 8.3 years, respectively), with and without DM2, participated in a three-month intensive exercise program. Before starting, participants were allocated into three subgroups (overweight, body mass index or BMI = 25–29.9; class 1 of obesity, BMI = 30–34.4; or class 2 (or superior) of obesity, BMI > 35). The international physical activity questionnaire (IPAQ-it) was used to evaluate participants’ baseline sitting time (SIT) and physical activity level (PAL). Stratified multiple analyses were performed using four subgroups of SIT level according to Ekelund et al., 2016 (low, 8 h/day of SIT) and three subgroups for PAL (high, moderate, and low). Health-related measures such as anthropometric variables, body composition, hematic parameters, blood pressure values, and functional capacities were studied at the beginning and at the end of the training period. An overall improvement of PAL was observed in the entire sample following the three-month intensive exercise program together with a general improvement in several health-related measures. The BMI group factor influenced the VO2 max variations, leg press values, triglycerides, and anthropometric variables, while the SIT group factor impacted the sitting time, VO2 max, glycemic profile, and fat mass. In this study, baseline PAL and SIT did not seem to influence the effects of an exercise intervention. The characteristics of our educational program, which also included a physical exercise protocol, allowed us to obtain positive results.

show abstract

Section: Discussionmentioning

confidence: 90%

Impact of BMI, Physical Activity, and Sitting Time Levels on Health-Related Outcomes in a Group of Overweight and Obese Adults with and without Type 2 Diabetes

Pippi

Cugusi

Bergamin

et al. 2022

JFMK

View full text Add to dashboard Cite

show abstract

“…Concurrent presence of obesity, sarcopenia, osteoporosis, and frailty can accelerate the functional decline, and interventions need to address all the factors together ( 41 ). Weight reduction without protein supplementation and resistance exercise can compromise the ability to maintain muscle mass and function leading to frailty, sarcopenia, and increased mortality ( 39 , 42 , 43 ). Skeletal muscle assessment and maintenance should be an integral part of all obesity clinics.…”

Section: Discussionmentioning

confidence: 99%

Association of central obesity and high body mass index with function and cognition in older adults

Merchant

Kit

Lim

et al. 2021

Endocrine Connections

View full text Add to dashboard Cite

Objective: To investigate the association of normal body mass index (BMI) with central obesity (CO), high BMI with CO, high BMI without CO, and normal BMI without CO, with function and cognition in older adults. Methods: Cross-sectional study involving 754 participants ≥ 65 years. Data collected include demographics, cognition and physical measurements. Results: Females had higher prevalence of high BMI with CO and lower prevalence of high BMI without CO than males (61.0% vs. 44.6% and 4.6% vs. 15.0% respectively). Within gender, CO groups, regardless of BMI, had lower mini-mental state examination (MMSE), handgrip strength (HGS) and Timed-Up-and-Go (TUG) scores. Overall, the high BMI without CO group had highest MMSE scores, HGS, and shortest TUG. Amongst males, HGS was significantly lower in the normal BMI with CO group (B -3.28, 95% CI -6.32 - -0.23, p=0.04). CO, regardless of normal/high BMI, had significantly longer TUG time (B 2.65, 95% CI 0.45 - 4.84, p = 0.02; B 1.07, 95% CI 0.25 - 1.88, p=0.01 respectively) than normal BMI without CO group. CO was associated with lower MMSE scores in both genders but significant only in males with normal BMI and CO (B -1.60, 95% CI -3.15 - -0.06, p=0.04). Conclusion: CO may be a better predictor of obesity and adverse outcomes in older adults. High BMI without CO was associated with better outcomes especially in males but require further validation. Prospective longitudinal studies are needed to ascertain the impact of BMI and/or CO on function, cognition, mortality and gender differences.

show abstract

“…The complete description of participant recruitment and randomization has been previously published (19). Briefly, 69 middle-aged (range: 50-64 years old; mean: 58.3 ± 0.5 years old) individuals (63 females and 6 males) with obesity (body mass index (BMI): 27.7 ± 0.4 kg/m 2 ; body fat: 41.5 ± 0.6%; waist circumference: 90.9 ± 1.0 centimeters) were randomly assigned into the control group (C), the exercise group (E) or the exercise combined with high-protein diet group (EP) and received 12 weeks of intervention.…”

Section: Participantsmentioning

confidence: 99%

“…Research has shown that both exercise and high-protein diets have potential to be beneficial for the cardiometabolic health of individuals with obesity (13,17). While many studies investigating the effects of exercise and nutrition found that highprotein diets/protein supplementation combined with exercise have stronger beneficial effects on skeletal muscle functions and physical functions than exercise alone (18,19), the knowledge about the effects of exercise alone or in combination with highprotein diet on markers of the cardiometabolic health is lacking. In this regard, this study aimed to examine the effects of exercise alone or in combination with high-protein diet on markers of cardiometabolic health in middle-aged adults with obesity.…”

Section: Introductionmentioning

confidence: 99%

Effects of Combined High-Protein Diet and Exercise Intervention on Cardiometabolic Health in Middle-Aged Obese Adults: A Randomized Controlled Trial

Chen

Hsu

Chien

et al. 2021

Front. Cardiovasc. Med.

Self Cite

View full text Add to dashboard Cite

Background: Obesity is the main risk factor of cardiovascular diseases (CVD) and metabolic diseases. The middle-aged population is the age group with the highest prevalence of obesity. Thus, improving cardiometabolic health is important to prevent CVD and metabolic diseases in middle-aged obese adults. The aim of this study was to examine the effects of exercise alone or in combination with a high-protein diet on markers of cardiometabolic health in middle-aged adults with obesity.Methods: Sixty-nine middle-aged adults with obesity were assigned randomly to the control group (C; n = 23), exercise group (E; n = 23), or exercise combined with high-protein diet group (EP; n = 23). Individuals in the E and EP groups received supervised exercise training and individuals in the EP group received high-protein diet intervention. Body composition (assessed by dual-energy X-ray absorptiometry), oral glucose tolerance test (OGTT), lipid profiles, and inflammatory markers were determined before and after 12 weeks of intervention. Insulin sensitivity index (ISI0,120) was calculated from values of fasting and 2-h insulin and glucose concentration of OGTT. Insulin-peak-time during the OGTT was recorded to reflect β-cell function. Analysis of covariance with baseline values as covariates was used to examine the effects of the intervention. The significant level was set at 0.05.Results: After 12 weeks of intervention, the E group had a greater percentage of individuals with early insulin-peak-time during the OGTT than that in the C and EP groups (p = 0.031). EP group had lower total cholesterol and triglycerides than that in the C group (p = 0.046 and 0.014, respectively). Within-group comparisons showed that the 2-h glucose of OGTT and C-reactive protein decreased in the EP group (p = 0.013 and 0.008, respectively) but not in the E and C groups; insulin sensitivity improved in the EP group (p = 0.016) and had a trend to improve in the E group (p = 0.052); and abdominal fat mass and total body fat mass decreased in both intervention groups (p < 0.05).Conclusion: Combined high-protein diet and exercise intervention significantly decreased fat mass and improved lipid profiles, insulin sensitivity, glucose tolerance, and inflammation in middle-aged adults with obesity.Clinical Trial Registration: Thai Clinical Trials Registry, TCTR20180913003, 13-09-2018.

show abstract

Effects of Exercise Alone or in Combination with High-Protein Diet on Muscle Function, Aerobic Capacity, and Physical Function in Middle-Aged Obese Adults: A Randomized Controlled Trial

Cited by 16 publications

References 37 publications

Impact of BMI, Physical Activity, and Sitting Time Levels on Health-Related Outcomes in a Group of Overweight and Obese Adults with and without Type 2 Diabetes

Impact of BMI, Physical Activity, and Sitting Time Levels on Health-Related Outcomes in a Group of Overweight and Obese Adults with and without Type 2 Diabetes

Association of central obesity and high body mass index with function and cognition in older adults

Effects of Combined High-Protein Diet and Exercise Intervention on Cardiometabolic Health in Middle-Aged Obese Adults: A Randomized Controlled Trial

Contact Info

Product

Resources

About