Effects of Estrogens Only on the Prostates of Aging Men

Kesteren, Paul van; Meinhardt, W.; Valk, Paul van der; Geldof, Albert A.; Megens, J.A.J.; Gooren, Louis

doi:10.1016/s0022-5347(01)65584-8

Cited by 44 publications

(17 citation statements)

References 15 publications

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“…Even more surprising in this setting is the strong expression of androgen receptor, which is in contrast with a report fi nding few androgen but ample estrogen and progesterone receptors detectable in the stroma and epithelium of the (small) prostate of aging male transsexuals [2] . In those patients, biopsies showed PSA expression in most cases.…”

Section: Discussioncontrasting

confidence: 58%

Does the Prostate Really Need Androgens to Grow? Transurethral Resection of the Prostate in a Male-to-Female Transsexual 25 Years after Sex-Changing Operation

Casella

Bubendorf²,

Schaefer³

et al. 2005

Urol Int

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Section: Discussioncontrasting

confidence: 58%

Does the Prostate Really Need Androgens to Grow? Transurethral Resection of the Prostate in a Male-to-Female Transsexual 25 Years after Sex-Changing Operation

Casella

Bubendorf²,

Schaefer³

et al. 2005

Urol Int

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“…the authors are grateful to Aging Today for extending their permission to cite copyrighted articles. van Kesteren et al (1996) Study and control groups, …”

Section: Resultsmentioning

confidence: 99%

“…Related themes included the dearth of educated health, mental health, and social care professionals (including the lack of geriatric care specialists who are familiar with trans physiology) (Berreth, 2003;Blank et al, 2009;Cook-Daniels, 2008a;Witten, 2002b); the denial of insurance coverage for trans-specific health care issues (Minter, 2002;Williams & Freeman, 2007;Witten & Eyler, 2006); the failure of care providers to differentiate trans issues from other health care issues and, by extension, the denial of insurance coverage for non-trans-specific health care issues (Berreth, 2003;Blank et al, 2009;Cook-Daniels, 2006;Haber, 2009;Knochel, 2011;OPHA, 2004;Williams & Freeman, 2007;Witten, 2003a;Witten & Eyler, 2006;Witten & Whittle, 2004); and, with minor exceptions, the lack of knowledge vis-à-vis the relationship between aging and gender transition (Berreth, 2003;Blank et al, 2009;Ferron, Young, Boulanger, Rodriguez, & Moreno, 2010;Haber, 2009;OPHA, 2004;Persson, 2009;Williams & Freeman, 2007;Witten, 2002b;Witten & Eyler, 2006;Witten & Whittle, 2004). Exceptions included articles exploring the long-term risks of contragender hormone use on bone density and prostate health (Mueller et al, 2005;van Kesteren et al, 1996;Witten & Eyler, 2007), and those exploring the impact of hormone treatment on hormone-related tumors (Mueller & Gooren, 2008;Persson, 2009). …”

Section: Health and Mental Healthmentioning

confidence: 99%

When Injustice Gets Old: A Systematic Review of Trans Aging

Finkenauer

Sherratt

Marlow

et al. 2012

Journal of Gay & Lesbian Social Services

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A lack of knowledge regarding the needs and experiences of trans and gender-nonconforming older adults contributes to and perpetuates the experiences of marginalization associated with being trans. Mitigating the conditions of marginalization-including those that are compounded by age-requires the production of trans aging knowledge. It was with the intent to produce such knowledge that this systematic review was undertaken. In so doing, five medical databases, eight social science databases, and two gray literature databases were searched. Text. A total of 436 titles and abstracts were independently reviewed. Of these, 106 full-text articles were retrieved; 34 met the inclusion criteria and were reviewed. The following themes were identified: 1. the methodological challenges associated with conducting research with trans and gender nonconforming older adults; 2. violence and abuse among trans and gender nonconforming older adults; 3. discriminatory policies and practices in health and mental health care;All authors contributed equally to this research and are listed in random order.

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“…In studies examining the role of estrogens in BPH development, it was proved that injecting DHT and estrogen together into castrated dogs caused prostatic hyperplasia, that DHT and estrogen had a synergistic effect with androgens, and that DHT and estrogen caused an increase in sensitization of the prostate to androgens by stimulating intraprostatic androgen receptor concentration [3,16,17]. However, estrogens without androgens cause prostatic shrinkage, instead of benign prostatic hyperplasia [18]. Positive correlation between BPH volume and levels of free testosterone, estradiol, and estriol is indication of the synergistic effect of estrogens and androgens in BPH development [1].…”

Section: Discussionmentioning

confidence: 99%