Effects of esmolol on haemodynamic response to CO₂ pneumoperitoneum for laparoscopic surgery

Abstract

Esmolol blunts the pressor response to induction and maintenance of pneumoperitoneum and may protect against renal ischaemia during pneumoperitoneum.

Oral clonidine: a simple yet effective and safe premedicant for hemodynamic stability during laparoscopic surgery and a calm post-operative period

“…2 Various drugs like opioids, ß blockers, nitroglycerine, magnesium sulphate etc. [3][4][5] have been tried to attenuate the PNP-associated haemodynamic instability but with limited success.…”

Estudo comparativo dos efeitos hemodinâmicos e ventilatórios da ventilação controlada a volume ou a pressão, em cães submetidos ao pneumoperitônio

“…Alguns estudos observaram um aumento na concentração plasmática do hormônio antidiurético (ADH) após a criação do pneumoperitônio 40,50,51 , suficiente para determinar o aumento da PAM e da SVR por vasoconstrição 40,52,53 . Acriação do pneumoperitônio com a insuflação de CO 2 leva a um aumento da concentração plasmática da renina [54][55][56] e da aldosterona 55 e da noradrenalina. Um estudo não observou alterações significativas nas concentrações da epinefrina, da norepinefrina e na atividade da renina plasmática, que pudessem estar correlacionadas ao aumento da PAM 40 .…”

“…Some studies have observed increased plasma concentration of antidiuretic hormone (ADH) after pneumoperitoneum 40,50,51 , enough to determine increased MBP and SVR by vasoconstriction 40,52,53 . CO 2 pneumoperitoneum leads to increased rennin [54][55][56] , aldosterone 55 and norepinephrine plasma concentration. A study has not observed significant epinephrine and norepinephrine concentrations, and plasma rennin activity changes which could be related to increased MBP 40 .…”

Hemodynamic Stress Response during Laparoscopic Cholecystectomy: Effect of Oral Administration of Moxonidine

“…Koivusalo et al, in their study, have shown that postoperative recovery after laparoscopic cholecystectomy was faster and uneventful when carbon dioxide was not used for pneumoperitoneum. They suggested that mechanical abdominal lift method without carbon dioxide insufflations is better for laparoscopic cholecystectomy may be the method of choice while considering laparoscopic cholecystectomy [10] . Fenton et al, in their review, observed that moxonidine acts centrally to reduce central and peripheral sympathetic activity, thus decreasing peripheral vascular resistance.…”