Effects of elevated ambient histamine level on survival, growth, sexual maturity and tissue histamine accumulation of the mysis Neomysis awatschensis and Neomysis japonica Nakazawa

Abstract

In Asia, trash fish have been routinely used in aquaculture often due to their local availability and lower costs compared to formulated feed. However, stale trash fish contain high levels of biogenic amines, which have been reported to be harmful to poultry and some aquatic animals. The present study elevated the effects of histamine levels in the water on survival, growth, sexual maturity and tissue histamine accumulation of two estuarine mysis, Neomysis awatschensis and Neomysis japonica Nakazawa. Newly hatched neonates of each mysis species were cultured in brackish water containing 0 (control), 5, 10 and 15 mg/L histamine until they reached sexual maturity. The results showed that compared to the control, survival of N. awatschensis was significantly lower in both 10 and 15 mg/L histamine treatments (69.5 and 62.5% vs. 86.5%). In the case of N. japonica Nakazawa, significantly lower survival was found for the 15 mg/L treatment (53.9% vs. 72.4%) (P \ 0.05). In a separate experiment, neonates of each mysis species were cultured individually (15 neonates/treatment) to assess the sub-lethal effects of histamine. It was shown that at the level of 15 mg/L, histamine had a significant impact on body weight and length of sexual matured N. japonica Nakazawa, which were only 87.7 and 78.7% of that of the control. However, no significant difference in intermolt period was detected. In the case of N. awatschensis, no significant differences in both body weight and length among treatments were detected (P [ 0.05) but the intermolt period was substantially prolonged at all histamine levels tested when compared to that of the control. Meanwhile, the timings required to reach sexual maturity for both male and female of the two mysis were generally increased with increasing histamine level, and such differences were often statistically significant (P \ 0.05). Compared to the control, the tissue histamine concentration of the mysis increased significantly at histamine concentrations of 10 and 15 mg/L for N. japonica Nakazawa (P \ 0.05). In the case of N. awatschensis, however, no significant differences were found among all treatments. Our findings indicate that histamine had clear negative effects on both mysis species although their responses and sensitivity appeared somewhat different. Our results suggest that further research is needed to assess the effects of water borne histamine on various aquatic animals.

The Good, the Bad, and the Lethal: Gene Expression and Metabolomics Reveal Physiological Mechanisms Underlying Chronic Thermal Effects in Mayfly Larvae (Neocloeon triangulifer)

“…Work from Morimoto et al (2001) suggested that brain histamine involves in modulating mouse feeding behavior. Yang and colleagues (Yang et al, 2012) showed that exogenous histamine had an effect on tissue histamine accumulation and also reduced body length, body weight and development time in the crustacean Neomysis japonica Nakazawa. Although the effect of histamine on feeding behavior and growth/development in insects has not been studied, it is possible that thermally driven increases in histamine reduces food intake in mayfly larvae, resulting in smaller body size and associated reduction in fecundity (Figure 4).…”

High Dietary Histamine Induces Digestive Tract Oxidative Damage in Juvenile Striped Catfish (Pangasianodon hypophthalmus)

“…As a toxic dietary component, histamine has attracted much attention from aquatic animal nutritionists in recent years. Previous studies have shown that dietary histamine significantly decreased the growth performance of the juvenile group ( Epinephelus coioides ) [ 35 ], mysis ( Neomysis japonica Nakazawa ) [ 36 , 37 ], American eels ( Anguilla rostrata ) [ 38 , 39 ], yellow catfish ( Pelteobagrus fulvidraco ) [ 29 ], and rainbow trout ( Oncorhynchus mykiss ) [ 40 ]. In this study, our data exhibited that dietary histamine below 60 mg/kg has limited effects on the growth of striped catfish, whereas dietary histamine above 120 mg/kg significantly decreased the growth, suggesting that the growth-inhibiting effect of dietary histamine was dose-dependent.…”