Effects of electrical stimulation on periodontal tissue remodeling in rats

Abstract

Electric stimulation may offer a novel approach to promote gingival tissue remodeling in periodontal lesions.

Microcurrent electrotherapy improves palatal wound healing: Randomized clinical trial

“…The results of the present study are in agreement with the histological data presented by Tomofuji et al., 14 who reported better tissue remodeling by using electrotherapy to treat periodontitis in a daily 10‐second electrical protocol (50 or 100 μA) for 2 weeks. Although there is a range of different protocols, as well as methods to conduct electrical stimulation on the dermis region, studies indicate a significant reduction of the RWA of decubitus ulcers with the use of electrotherapy in comparison with conventional treatments 27–30 .…”

“…Microcurrent electrotherapy, that is, using low level (<1 mAmp) currents, has been used in the medical field to treat chronic ulcers 12,13 . In dentistry, studies applied electric currents in animal models to treat periodontal disease, stimulate periodontal regeneration, and accelerate orthodontic movement 14–17 . The results suggest that repair and regeneration of periodontal injuries may benefit from electric stimulation.…”

“…However, despite documented benefits of electrotherapy for wound closure in medicine 12,13,18 and promising results on periodontal healing described in animal models, 14–17 to the best of our knowledge, there is a lack of clinical studies designed to evaluate the clinical effects of electrotherapy in periodontal procedures and mucosal wound healing.…”

Endogenous Mechanisms of Craniomaxillofacial Repair: Toward Novel Regenerative Therapies

“…While poorly-healing oral wounds lack a definitive treatment, several avenues for improving impaired oral healing are currently being explored. These strategies-which include electrical stimulation of tissue, photobiomodulation therapy, and growth factor treatments-have shown promise for improving clinical healing of chronic skin wounds [94][95][96] but have been less explored for oral healing. Current research seeks to determine whether these therapeutic modalities can also be useful for problematic intraoral wound healing.…”

“…Current research seeks to determine whether these therapeutic modalities can also be useful for problematic intraoral wound healing. For instance, rodent studies suggest that electrical stimulation may also be useful for supporting intraoral (e.g., palatal, gingival) wound healing [ 94 , 97 ]. Photobiomodulation therapy has also been shown to improve healing in patients following palatal graft harvest [ 98 ].…”