Effects of Ecklonia arborea or Silvetia compressa algae intake on serum lipids and hepatic fat accumulation in Wistar rats fed hyperlipidic diets

Acevedo-Pacheco, Laura; Garza, Ana Rocío Múzquiz de la; Elena, P. M.; Gutiérrez-Uribe, Janet A.; Trejo-Chávez, Armando; Cruz‐Suárez, Lucía Elizabeth; Serna‐Saldívar, Sergio O.

doi:10.1016/j.algal.2020.101946

Cited by 1 publication

(2 citation statements)

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“…In addition, the group fed the S. compressa extract had lower levels of LDL-c. Liver histology showed a reduction in steatosis in the group fed S. compressa vs. E. arborea extract. This suggests S. compressa as a resource for the reduction of serum cholesterol and liver tissue damage [180].…”

Section: Macroalgal Phytochemicals Affecting Cholesterol Metabolism I...mentioning

confidence: 96%

“…In addition, macroalgae have the reported ability to absorb cholesterol and excrete it from the body through the feces. A recent in vivo study of rats fed a 20% HFD and an additional 2.5% of extracts from the macroalgae Ecklonia arborea or Silvetia compressa showed different results for the two algae with respect to cholesterol levels and liver histology [180]. S. compressa caused an 18% decrease in total cholesterol, whereas E. arborea increased cholesterol levels by 5.8% compared to the control rats.…”

Section: Macroalgal Phytochemicals Affecting Cholesterol Metabolism I...mentioning

confidence: 98%

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Regulation of Cholesterol Metabolism by Phytochemicals Derived from Algae and Edible Mushrooms in Non-Alcoholic Fatty Liver Disease

Eilam

Pintel

Khattib

et al. 2022

IJMS

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Cholesterol synthesis occurs in almost all cells, but mainly in hepatocytes in the liver. Cholesterol is garnering increasing attention for its central role in various metabolic diseases. In addition, cholesterol is one of the most essential elements for cells as both a structural source and a player participating in various metabolic pathways. Accurate regulation of cholesterol is necessary for the proper metabolism of fats in the body. Disturbances in cholesterol homeostasis have been linked to various metabolic diseases, such as hyperlipidemia and non-alcoholic fatty liver disease (NAFLD). For many years, the use of synthetic chemical drugs has been effective against many health conditions. Furthermore, from ancient to modern times, various plant-based drugs have been considered local medicines, playing important roles in human health. Phytochemicals are bioactive natural compounds that are derived from medicinal plants, fruit, vegetables, roots, leaves, and flowers and are used to treat a variety of diseases. They include flavonoids, carotenoids, polyphenols, polysaccharides, vitamins, and more. Many of these compounds have been proven to have antioxidant, anti-inflammatory, antiobesity and antihypercholesteremic activity. The multifaceted role of phytochemicals may provide health benefits to humans with regard to the treatment and control of cholesterol metabolism and the diseases associated with this disorder, such as NAFLD. In recent years, global environmental climate change, the COVID-19 pandemic, the current war in Europe, and other conflicts have threatened food security and human nutrition worldwide. This further emphasizes the urgent need for sustainable sources of functional phytochemicals to be included in the food industry and dietary habits. This review summarizes the latest findings on selected phytochemicals from sustainable sources—algae and edible mushrooms—that affect the synthesis and metabolism of cholesterol and improve or prevent NAFLD.

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Section: Macroalgal Phytochemicals Affecting Cholesterol Metabolism I...mentioning

confidence: 96%

Section: Macroalgal Phytochemicals Affecting Cholesterol Metabolism I...mentioning

confidence: 98%

Regulation of Cholesterol Metabolism by Phytochemicals Derived from Algae and Edible Mushrooms in Non-Alcoholic Fatty Liver Disease

Eilam

Pintel

Khattib

et al. 2022

IJMS

View full text Add to dashboard Cite

show abstract

Effects of Ecklonia arborea or Silvetia compressa algae intake on serum lipids and hepatic fat accumulation in Wistar rats fed hyperlipidic diets

Cited by 1 publication

References 52 publications

Regulation of Cholesterol Metabolism by Phytochemicals Derived from Algae and Edible Mushrooms in Non-Alcoholic Fatty Liver Disease

Regulation of Cholesterol Metabolism by Phytochemicals Derived from Algae and Edible Mushrooms in Non-Alcoholic Fatty Liver Disease

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