Effects of e‐health interventions on health outcomes in patients with rheumatoid arthritis: a systematic review and meta‐analysis

Abstract

Aims and Objectives To evaluate the effects of e‐health interventions on disease activity, self‐efficacy, pain and quality of life among patients with rheumatoid arthritis (RA). Background Prior systematic reviews have only reported the quality and features of e‐health interventions in patients with RA. However, the effect of e‐health interventions in patients with RA is unclear. Design Systematic review and meta‐analysis. Methods This review was conducted following the PRISMA guideline. We searched 5 databases, including PubMed, EMBASE, CINAHL, Scopus and the Cochrane library. The risk of bias was assessed using the Cochrane risk of bias tool. The quality of the evidence was assessed via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) criteria. Using a random‐effects model adopted the standardised mean difference (SMD) with a 95% confidence interval (CI). A chi‐squared test and an I2 test were used to assess heterogeneity. Subgroup analyses were conducted based on different controls. Results A total of 9 randomised control trials were included in this study. Compared with the control group, disease activity of the e‐health group significantly decreased (SMD with 95% CI: −.17 [−.30, −.04], p = .01, I2 = 1%). Meanwhile, trials with usual care control had a larger effect on disease activity (SMD with 95% CI: −.21 [−.40, −.02], p = .03, I2 = 38%). The effect of e‐health interventions on self‐efficacy was controversial; pain and quality of life were negative in the currently included studies. The quality of evidence was rated as low for disease activity and very low for pain, self‐efficacy and quality of life. Conclusions The effect of e‐health interventions on disease activity was statistically significant. More well‐designed randomised controlled trials are still needed to verify the effects in the future. Relevance to clinical practice This study shows the potential value of e‐health in improving health outcomes in patients with RA.

Effects of eHealth Interventions on Quality of Life and Psychological Outcomes in Cardiac Surgery Patients: Systematic Review and Meta-analysis

“…Electronic intervention was reported to be ineffective for depression in 2 studies [ 51 , 60 ], whereas 3 articles [ 54 , 55 , 59 ] provided mixed conclusions. There were mixed results regarding the effect of pain relief, with some studies [ 50 , 51 ] indicating no effect on pain relief, and others [ 55 , 61 ] reporting the opposite. Seven studies reported on patient compliance: 2 studies [ 51 , 62 ] showed no statistical significance in improving patient compliance, 3 studies [ 63 - 65 ] showed a positive impact, and according to the remaining 2 studies [ 66 , 67 ], the impact was uncertain.…”

“…Among the published systematic evaluations, studies on the application of electronic interventions included patients with cancer, respiratory diseases, and arthritis. In terms of quality of life, 3 studies [49][50][51] reported that electronic interventions were ineffective, but 7 [52][53][54][55][56][57][58] reported improvement in quality of life. Two articles [51,57] reported that electronic intervention was ineffective in relieving anxiety, and another [59] showed mixed views.…”

“…In addition, we found that the effectiveness of electronic interventions may be related to the disease type. eHealth interventions showed positive effects on the outcome of some patients [52][53][54][55], but studies reporting on patients with cancer [49] and patients with arthritis [50,51] reported negative results.…”