“…Although several studies have been conducted to investigate the efficacy and safety of modified FOLFIRINOX regimens, the appropriate FOLFIRINOX regimen remains unclear. (5)(6)(7)(8)(9) Prospective studies of modified FOLFIRINOX regimens are being conducted in Japan, Europe and the USA. In the future, we anticipate the establishment of a modified FOLFIRINOX regimen that can control toxicity successfully without compromising efficacy.…”