Effects of disodium cromoglycate on cationic exchange of deoxygenated sickle cells

Bizumukama, Léonidas; Ferster, Alina; Gulbis, Béatrice; Kumps, Alain; Cotton, Frédéric

doi:10.1016/j.ejphar.2011.05.007

Cited by 1 publication

(2 citation statements)

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“…Altogether, these studies presented preliminary data that require further investigations about these compounds in order to, in a near future, be used on the production of designing medicines. Currently, a few natural-based active compounds are already available in the market, such as ipratropium bromide, theophylline, epinephrine, and sodium cromoglycate [226,[228][229][230][231].…”

Section: Conclusion: Widely Used Active Pharmaceutical Ingredients Frmentioning

confidence: 99%

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Use of Natural Products in Asthma Treatment

Amaral-Machado

Oliveira

Moreira-Oliveira

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Asthma, a disease classified as a chronic inflammatory disorder induced by airway inflammation, is triggered by a genetic predisposition or antigen sensitization. Drugs currently used as therapies present disadvantages such as high cost and side effects, which compromise the treatment compliance. Alternatively, traditional medicine has reported the use of natural products as alternative or complementary treatment. The aim of this review was to summarize the knowledge reported in the literature about the use of natural products for asthma treatment. The search strategy included scientific studies published between January 2006 and December 2017, using the keywords “asthma,” “treatment,” and “natural products.” The inclusion criteria were as follows: (i) studies that aimed at elucidating the antiasthmatic activity of natural-based compounds or extracts using laboratory experiments (in vitro and/or in vivo); and (ii) studies that suggested the use of natural products in asthma treatment by elucidation of its chemical composition. Studies that (i) did not report experimental data and (ii) manuscripts in languages other than English were excluded. Based on the findings from the literature search, aspects related to asthma physiopathology, epidemiology, and conventional treatment were discussed. Then, several studies reporting the effectiveness of natural products in the asthma treatment were presented, highlighting plants as the main source. Moreover, natural products from animals and microorganisms were also discussed and their high potential in the antiasthmatic therapy was emphasized. This review highlighted the importance of natural products as an alternative and/or complementary treatment source for asthma treatment, since they present reduced side effects and comparable effectiveness as the drugs currently used on treatment protocols.

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Section: Conclusion: Widely Used Active Pharmaceutical Ingredients Frmentioning

confidence: 99%

“…Furthermore, sodium cromoglycate, a drug obtained from the khellin bioactive extracted from Ammi visnaga (L) Lamk, has been used as a bronchodilator based on its ability of inhibiting mast cell degranulation, which enabled its use on the asthma treatment [226,230].…”

Section: Conclusion: Widely Used Active Pharmaceutical Ingredients Frmentioning

confidence: 99%