In the effective field theory framework, quantum gravity can induce effective dimension-5 operators, which have important impacts on grand unified theories. Interestingly, one of main effects is the modification of the usual gauge coupling unification condition. We investigate the gauge coupling unification in E 6 under modified gauge coupling unification condition at scales M X in the presence of one or more dimension-5 operators. It is shown that non-supersymmetric models of E 6 unification can be obtained and can easily satisfy the constraints from the proton lifetime. For constructing these models, we consider several maximal subgroups H=SO(10)×U(1), H=SU(3)×SU(3)×SU (3), and H=SU(2)×SU(6) of E 6 and the usual breaking chains for a specific maximal subgroup, and derive all of the Clebsch-Gordan coefficients s z r , F ( ) associated with E 6 breaking to the standard model, which are given in appendix A.