Effects of dim light at night in C57BL/6J mice on recovery after spinal cord injury
John C. Aldrich,
Ashley R. Scheinfeld,
Sydney E. Lee
et al.
Abstract:Spinal cord injury (SCI) can cause long-lasting locomotor deficits, pain, and mood disorders. Anatomical and functional outcomes are exacerbated by inflammation after SCI, which causes secondary damage. One promising target after SCI is manipulating the circadian system, which optimizes biology and behavior for time of day, including neuroimmune responses and mood-related behaviors. Circadian disruption after SCI is likely worsened by a disruptive hospital environment, which typically includes dim light-at-nig… Show more
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