Effects of Different Surface Functionalizations of Silica Nanoparticles on Mesenchymal Stem Cells
Zhihao Huang,
Zhongqi Zhou,
Qiaoyuan Ye
et al.
Abstract:Physicochemical properties of nanoparticles, such as particle size, surface charge, and particle shape, have a significant impact on cell activities. However, the effects of surface functionalization of nanoparticles with small chemical groups on stem cell behavior and function remain understudied. Herein, we incorporated different chemical functional groups (amino, DETA, hydroxyl, phosphate, and sulfonate with charges of +9.5, + 21.7, −14.1, −25.6, and −37.7, respectively) to the surface of inorganic silica… Show more
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