Effects of different intensities of aerobic exercise on proteinuria in hypoxia and normoxia conditions in young football players

Peeri, Maghsoud; Kohanpour, Mohammad-Ali; Sanavi, Suzan; Matinhomaee, Hasan; Mirsepasi, Mona

doi:10.1016/j.dialis.2011.10.001

Cited by 4 publications

(2 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The proteins found in urine are mostly related to albumin, whereas the blood proteins are mostly ascribed to albumin and globulin. Elevated levels of protein in urine could be related to temporary health conditions, such as pregnancy [39], stress [40], infections [41], or heavy exercises [42]. High level of total protein in blood could be related to kidney or liver diseases [43].…”

Section: Colorimetric Detection Of Glucose Nitrite and Protein In Smentioning

confidence: 99%

A simple method to produce 2D and 3D microfluidic paper-based analytical devices for clinical analysis

Oliveira

Camargo

Pesquero

et al. 2017

Analytica Chimica Acta

112

View full text Add to dashboard Cite

This paper describes the fabrication of 2D and 3D microfluidic paper-based analytical devices (μPADs) for monitoring glucose, total protein, and nitrite in blood serum and artificial urine. A new method of cutting and sealing filter paper to construct μPADs was demonstrated. Using an inexpensive home cutter printer soft cellulose-based filter paper was easily and precisely cut to produce pattern hydrophilic microchannels. 2D and 3D μPADs were designed with three detection zones each for the colorimetric detection of the analytes. A small volume of samples was added to the μPADs, which was photographed after 15 min using a digital camera. Both μPADs presented an excellent analytical performance for all analytes. The 2D device was applied in artificial urine samples and reached limits of detection (LODs) of 0.54 mM, 5.19 μM, and 2.34 μM for glucose, protein, and nitrite, respectively. The corresponding LODs of the 3D device applied for detecting the same analytes in artificial blood serum were 0.44 mM, 1.26 μM, and 4.35 μM.

show abstract

Section: Colorimetric Detection Of Glucose Nitrite and Protein In Smentioning

confidence: 99%

A simple method to produce 2D and 3D microfluidic paper-based analytical devices for clinical analysis

Oliveira

Camargo

Pesquero

et al. 2017

Analytica Chimica Acta

112

View full text Add to dashboard Cite

show abstract

“…The coupling between desaturation and attenuated postexercise α1-AGP excretion in HYP observed in this study supports earlier cycling-based studies that have demonstrated similar reductions ( 7 ) or unchanged postexercise excretion in hypoxia ( 28 ). The present observations were attributed to concomitant reductions in exercise performance known to accompany hypoxic exercise ( 29 ), which have, in part, been attributed to reductions in blood flow to the working limbs ( 30 ). It is suggested that in response to vigorous hypoxia (i.e., maximal exercise in HYP), an alteration in the redistribution of blood flow occurs, which promotes a balance between glomerular blood flow and pressure ( 31 ) that does not favor proteinuria to the same extent as NOR exercise [or lower exercise intensities ( 32 )].…”

Section: Discussionmentioning

confidence: 66%

Postexercise urinary alpha-1 acid glycoprotein is not dependent on hypoxia

Joyce

Balanos

Bradley

et al. 2022

Journal of Applied Physiology

View full text Add to dashboard Cite

Introduction: Proteinuria is a transient physiologic phenomenon that occurs with a range of physical activities and during ascent to altitude. Exercise intensity appears to dictate the magnitude of post-exercise proteinuria; however, evidence also indicates possible contributions from exercise-induced hypoxemia or reoxygenation. Utilizing an environmental hypoxic chamber, this crossover designed study aimed to evaluate urinary alpha-1 acid glycoprotein (α1-AGP) excretion pre/post exercise performed in hypoxia and normoxia. Methods: Sixteen individuals underwent experimental sessions in normoxia (NOR, 20.9% O2) and hypoxia (HYP, 12.0% O2). Sessions began with a 2-hour priming period before completing a graded maximal exercise test (GXT) on a cycle ergometer, which was followed by continuation of exposure for an additional 2 hours. Physiologic responses (i.e., blood pressure, heart rate, and peripheral oxygenation), Lake Louise Scores, and urine specimens (analyzed for albumin and α1-AGP) were collected pre- and post-exercise (after 30, 60, and 120 minutes). Results: Peak power output was significantly reduced in HYP (193 ± 45 W) compared to NOR (249 ± 59 W, p < 0.01). Post-exercise urinary α1-AGP was greater in NOR (20.04 ± 14.84 μg•min-1) compared to HYP (15.08 ± 13.46 μg•min-1), albeit the difference was not significant (p > 0.05). Changes in urinary α1-AGP from pre- to post-30 minutes were not related to physiologic responses or performance outcomes observed during GXT in NOR or HYP. Conclusion: Despite profound systemic hypoxemia with maximal exercise in hypoxia, post-exercise α1-AGP excretion was not elevated above levels observed following normoxic exercise.

show abstract