Effects of Different Exercise Therapies on Balance Func-tion and Functional Walking Ability in Multiple Sclero-sis Disease Patients―A Network Meta-Analysis of Randomized Controlled Trials

Effects of exercise in people with multiple sclerosis: a systematic review and meta-analysis

“…Our results showed that exercise significantly improved walking ability (MSWS-12) and walking endurance (6MWT) in people with MS, which was in agreement with previous studies, showing that aerobic exercise, aquatic exercise, virtual reality training, and assisted gait training significantly improved walking ability ( 67 – 69 ), as well as that Pilates, aerobic exercise, resistance exercise, high-intensity training, and intermittent walking training significantly improved walking endurance in people with MS ( 28 , 68 , 70 – 72 ). Furthermore, fast-velocity concentric resistance training may have a greater effect on walking endurance with greater neural adaptations in a shorter period of time ( 28 ).…”

“…Our study showed that exercise significantly improved balance function (TUG and BBS) in people with MS, which was consistent with a previous study ( 13 ), showing that the combination of resistance and aerobic exercise training is effective in improving balance in people with MS and supports functional and psychological therapeutic effects through exercise. In addition, a meta-analysis showed that yoga was the best intervention to improve static and dynamic balance, and aquatic training was the best intervention to improve walking ability in people with MS ( 67 ). The mechanisms by which exercise improves balance may be that exercise improves neurological control of muscles, increases unconscious deliberate muscle responses to dynamic joint stabilization signals, and enhances core area muscle strength to strengthen body stability.…”