Effects of Different Exercise Modalities on Sex Hormones and Anxiety and Depression in Female Drug Addicts

Abstract

To explore the effects of different exercise modes on sex hormones and anxiety and depression of female drug addicts. METHODS: A random sampling method was used to include 30 female drug addicts who met the criteria from the Female Compulsory Drug Rehabilitation Center in Nanan District, Chongqing, China, who were randomly divided into a yoga group (n=10), a physical fitness group (n=10), and a control group (n=10), and underwent intervention training for a period of 12 weeks, 3 times per week, 1 h each time. The subjects' serum luteinizing hormone (LH), pituitary prolactin (PRL), and estradiol (E2) levels were quantitatively detected and analyzed by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) before and after the intervention. RESULTS: Changes in sex hormone levels of female drug addicts showed that serum luteinizing hormone (LH), pituitary prolactin (PRL), and estradiol (E2) levels were reduced compared with those of the control group. 12 weeks of different training interventions were able to regulate sex hormones, and hormone levels of the Yoga group and the Physical Fitness group were all significantly reduced (P<0.01), and the Yoga group was significantly lower than the Physical Fitness group and the control group (P<0.05); and reduced anxiety (HAHA), and reduced anxiety (HAHA). And reduce anxiety (HAHA) and depression (SDS) status.