Effects of dietary supplementation with palygorskite on intestinal integrity in weaned piglets

Zhang, Junmin; Lv, Yunfeng; Tang, Chaohua; Wang, Xiu-Qi

doi:10.1016/j.clay.2013.10.009

Cited by 47 publications

(62 citation statements)

References 21 publications

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“…On the other hand, the large specific surface area of Pal allows it to become distributed over the surface of the gut mucosa to form a barrier immediately after ingestion (Slamova et al, 2011;Lv et al, 2015). Pal can protect the intestinal mucosa by interacting with digestive mucus (Guarino et al, 2009;Zhang et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…The high surface area, the charge on the lattice, and the inverted structure confer properties of absorption, cation exchange capacity, and adhesive ability (Murray, 2000). These properties make Pal widely useful in the animal industry as an aflatoxin adsorbent, a tannin adsorbent, and an excipient in pharmaceutical preparations, and as an antacid, gastrointestinal protector, and anti-diarrheic (Isabel Carretero and Pozo, 2009;2010;Zhang et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Copper-modified palygorskite is effective in preventing and treating diarrhea caused by Salmonella typhimurium

Yao

et al. 2017

J. Zhejiang Univ. Sci. B

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Abstract:The aim of this research was to develop effective alternative therapies to reduce antibiotic use in animal agriculture. In this study, the efficacy of copper-modified palygorskite (CM-Pal) in preventing diarrhea caused by Salmonella was specifically examined both in vitro and in vivo. The CM-Pal was prepared with palygorskite (Pal) and copper nitrate. The antibacterial activity of the CM-Pal was detected by comparing the differences in cell numbers on plate count agar before and after adding the CM-Pal to Salmonella typhimurium cultures. Seventy ICR mice were then allocated into seven groups. Five groups (the treatment groups) were infected with S. typhimurium by intraperitoneal (i.p.) injection and were given Pal, CM-Pal, montmorillonite powder, gentamicin, and physiological saline, respectively. One group (the prevention group) was given CM-Pal before infection with S. typhimurium. Another group (the uninfected group) was not infected with S. typhimurium. The effects of Pal, CM-Pal, montmorillonite powder, and gentamicin on the treatment or prevention of diarrhea in the mice were examined by stool studies, fecal scoring, and assessment of growth performance and villus height. The CM-Pal had satisfactory anti-bacterial properties in vitro: the antibacterial rate was 100% after 2 h incubation with S. typhimurium NJS1 cultures (1×10 6 colony-forming units (CFU)/ml). In the in vivo experiment, the CM-Pal exerted superior effects in the treatment and prevention of diarrhea in mice compared with Pal, montmorillonite powder, and gentamicin. In the CM-Pal group, no mice showed signs of diarrhea at 24 h post infection (p.i.), and all mice fully recovered from infection. However, the Pal group, montmorillonite group, and gentamicin group only recovered after 48, 48, and 96 h, respectively. The villus height level in the CM-Pal treatment group recovered at 3 d p.i. However, the recovery time of the other groups was longer (at least 5 d). The CM-Pal prevention group had a better effect on weight gain than the other groups. This study suggested that CM-Pal may be an effective alternative to conventional antibiotics for the treatment and prevention of animal diarrhea caused by Salmonella.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Copper-modified palygorskite is effective in preventing and treating diarrhea caused by Salmonella typhimurium

Yao

et al. 2017

J. Zhejiang Univ. Sci. B

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“…It has been reported that palygorskite incorporation alleviated the adverse damage induced by aflatoxin-contaminated diets in weanling pigs [2]. Also, Zhang et al [3] found that palygorskite enhanced growth performance, decreased diarrhea rate, and improved intestinal morphology and barrier function of weaned piglets. In broilers, dietary 1.0 % palygorskite incorporation, used as a pellet binder, can increase hardness of pellets without adverse effect on the growth performance of broilers during a 6-week study [4].…”

Section: Introductionmentioning

confidence: 97%

Effects of Palygorskite Inclusion on the Growth Performance, Meat Quality, Antioxidant Ability, and Mineral Element Content of Broilers

Cheng

Chen

et al. 2016

Biol Trace Elem Res

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The present study was conducted to investigate different levels of palygorskite supplementation on the growth performance, meat quality, muscular oxidative status, and mineral element accumulation of broilers. One hundred ninety-two 1-day-old Arbor Acres broiler chicks were allocated to four dietary treatments with six replicates of eight chicks per replicate. Birds in the four treatments were given a basal diet supplemented with 0, 5, 10 and 20 g/kg palygorskite for 42 days, respectively. Compared with the control group, neither 5 g/kg nor 10 g/kg palygorskite inclusion affected growth performance of broilers during the 42-day study (P > 0.05). However, the highest level of palygorskite supplementation at 20 g/kg increased feed/gain ratio (F/G) of broilers (P < 0.001). Yellowness (P < 0.001) and redness (P = 0.003) of breast muscle and yellowness of leg muscle (P = 0.001) were decreased by palygorskite supplementation at the levels of 10 g/kg and especially 20 g/kg. In addition, redness of leg muscle was also reduced by the inclusion of 20 g/kg palygorskite (P = 0.009). In contrast, malonaldehyde (MDA) accumulation in the breast muscle was significantly increased by 20 g/kg palygorskite supplementation (P < 0.001). Supplementation of palygorskite at either 10 or 20 g/kg significantly decreased lead (Pb) accumulation in the breast (P = 0.001) or thigh (P = 0.045) and copper (Cu) accumulation in the breast (P = 0.022). In conclusion, growth performance, meat color, and antioxidant capacity of meat would reduce with the increasing level of palygorskite supplementation, whereas a higher level of palygorskite (10 or 20 g/kg) can alter mineral element accumulations in muscles as evidenced by reduced muscular Cu and Pb contents.

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“…A thermal or acid treatment enhances its sorptive properties and surface area (Alvarez et al, 2011). Dietary supplementation with 2000 mg/kg palygorskite improved growth performance and reduced the incidence of diarrhea in weaned piglets (Zhang et al, 2013). In lactating cows, palygorskite supplementation at levels up to 10 kg/t, improved cow milk yield, increased milk protein yield and decreased milk colony forming units (Bampidis et al, 2014).…”

mentioning

confidence: 99%

Effects of attapulgite dietary supplementation on sow performance in two commercial farms in Greece

Kanoulas

Papadopoulos

Arsenos

et al. 2018

J Hellenic Vet Med Soc

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The present study investigated the effects of attapulgite supplementation in sow diets during gestation and lactation on sow performance. The study comprised two reproductive phases (cycles) in two commercial farrow to finish farms: Farm A (capacity: 550 sows) and Farm B (capacity: 220 sows). The treatment groups were: a) control group (CN): the sows were fed a common gestation or lactation diet; b) attapulgite group (AT): the sows were fed the CN diet supplemented with attapulgite at 0,7% level; c) attapulgite plus group (AT+): the sows were fed the CN diet supplemented with attapulgite (0.7%) and a mix of enzymes, live yeast and amino acids (0.1%), at a total of 0.8% level. Within each cycle the sows included per treatment were: 24 for Farm A; 12 for Farm B. Initially data were analyzed per cycle and per each farm. Data from sows that completed both cycles within each farm, were analyzed by repeated measures analysis. Regarding sow parameters, sow body weight loss during lactation tended to be greater in AT sows compared to CN sows during cycle 1 in Farm B and was greater in AT and AT+ than CN sows in Farm A that completed both cycles (P=0.063 and P=0.023, respectively). A greater litter size 24h postpartum was observed in favour of AT compared to CN group during cycle 1 in Farm A and in sows that completed both cycles in Farm A (P=0.001 and P= 0.011, respectively). Litter size at weaning was greater in sows from the AT group than CN during cycle 1 and 2 in Farm A, in cycle 1 in Farm B and in sows that completed both cycles in Farm A (P=0.004, P=0.037, P=0.037, and P=0.022, respectively). Piglet weight at weaning and average daily gain during lactation were greater in AT group than CN and AT+ in sows that completed both cycles in Farm A (P=0.049 and P=0.040 respectively). Notable similar effects, although not statistically significant, were also observed in Farm B. This field study suggests that attapulgite supplementation in sow diets can improve performance indexes. Further research should investigate the underlying mechanisms involved.

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Effects of dietary supplementation with palygorskite on intestinal integrity in weaned piglets

Cited by 47 publications

References 21 publications

Copper-modified palygorskite is effective in preventing and treating diarrhea caused by Salmonella typhimurium

Copper-modified palygorskite is effective in preventing and treating diarrhea caused by Salmonella typhimurium

Effects of Palygorskite Inclusion on the Growth Performance, Meat Quality, Antioxidant Ability, and Mineral Element Content of Broilers

Effects of attapulgite dietary supplementation on sow performance in two commercial farms in Greece

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