Effects of Dietary Supplementation with Fish Scales-Derived Collagen Peptides on Skin Parameters and Condition: A Randomized, Placebo-Controlled, Double-Blind Study

Koizumi, Seiko; Inoue, Naoki; Shimizu, Mitsuharu; Kwon, Chang‐Ju; Kim, Hwa-Young; Park, Kyoung Sik

doi:10.1007/s10989-017-9626-0

Cited by 23 publications

(27 citation statements)

References 13 publications

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“…The oral supplementation product was composed of HC with a mix of vitamins A, C, E, and zinc [126]. HC from tilapia fish scale ( Oreochromis mosambicus ) in the form of 20 mL beverage (Nitta Gelatin Inc ® ., India) was consumed by healthy women aged 30–60 years over 12 weeks, after this time the result was enhanced facial skin moisture [127]. HC drinking ampoules with fruit extract, Vit C, E, zinc, and biotin ELASTEN ® were supplied to 36 healthy women aged 35 years or older for 12 weeks and their skin showed higher hydration, elasticity, smoothness and density [123].…”

Section: Hydrolyzed Collagen: Sources and Applicationsmentioning

confidence: 99%

Hydrolyzed Collagen—Sources and Applications

et al. 2019

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Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3–6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC can be extracted from different sources such as bovine or porcine. These sources have presented health limitations in the last years. Recently research has shown good properties of the HC found in skin, scale, and bones from marine sources. Type and source of extraction are the main factors that affect HC properties, such as molecular weight of the peptide chain, solubility, and functional activity. HC is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. The present review presents the different types of HC, sources of extraction, and their applications as a biomaterial.

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Section: Hydrolyzed Collagen: Sources and Applicationsmentioning

confidence: 99%

Hydrolyzed Collagen—Sources and Applications

et al. 2019

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“…Further screening by title and/or abstract resulted in removal of 6500 items. Finally, full texts of the 31 remained items were assessed for eligibility and 10 publications were included in this review 2,3,12‐15,25‐28 . Table 1 shows the features of selected studies which assessed the effect of collagen (intact or hydrolyzed) supplementation on skin health or aging parameters.…”

Section: Resultsmentioning

confidence: 99%

“…were included in this review. 2,3,[12][13][14][15][25][26][27][28] Table 1 shows the features of selected studies which assessed the effect of collagen (intact or hydrolyzed) supplementation on skin health or aging parameters.…”

Section: Quality Assessmentmentioning

confidence: 99%

“…14 When collagen molecules undergo different degradative processes including physical, chemical, and biological procedures, collagen hydrolysates (CH) are formed due to the hydrolysis of collagen strands' molecular bonds. 15 Compared to the intact form of collagen, hydrolyzed collagen has less antigenic trait. 16 Also, when interventional studies use intact collagen, the intervention dose is reduced by 2000 times.…”

Section: Introductionmentioning

confidence: 99%

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Collagen supplementation for skin health: A mechanistic systematic review

Barati

Jabbari

Navekar

et al. 2020

J of Cosmetic Dermatology

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Background Over the last decade, many researchers tried to evaluate the effects of collagen supplements on skin aging and surprisingly revealed that the interventions improved skin aging parameters without any inconsistency. Aim This systematic review assesses the literature regarding the effects of collagen supplements on skin health parameters in healthy and patient subjects, focusing on mechanisms of action. Methods At the first step of search in the databases, 9057 items were obtained. After removal of duplicate items, 6531 publications remained. Further screening by title and/or abstract resulted in removal of 6500 items. Finally, full texts of the 31 remained items were assessed for eligibility and 10 publications were included in this review. Results The evidences obtained from these systematic reviews indicated that oral administration of intact or hydrolyzed collagen improves clinical manifestation of skin health. Almost all of the included studies reported the beneficial effects of collagen supplementation, and no inconsistencies have been seen in this regard between studies. Conclusions In this systematic review, three different mechanisms of action were clarified for the intervention. Direct effects of collagen peptides on fibroblasts, M2‐like macrophages, and oral tolerance‐related mechanisms are the possible mechanisms for the beneficial effects of collagen supplementation.

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“…Some previous studies had the objective of demonstrating that collagen hydrolysates can influence the collagen turnover/balance of different tissues, such as skin or cartilage, and that applying or ingesting collagen hydrolysates may be beneficial for preventing aging of skin or cartilages [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture

et al. 2018

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Fish discards and subproducts may represent an important source of raw material, not only for the food industry, but for other different kind of industries, such as the nutraceutical and cosmetic industries. Collagen, which is mainly obtained from animal skins, is an important structural protein in the animal kingdom having many different applications. It is well known that fish skins constitute a significant subproduct in the fishery industry, especially in the case of some species, where fish skins may represent up to 20% of the total body weight of fish. Peptides from collagen hydrolysates have been described to be useful for preventing skin aging and osteoarthritis, however, the mechanism for these biological activities is not well known. Fibroblasts are the main cell types involved in the collagen synthesis, and in the present work, human dermal fibroblasts have been exposed to the treatment of collagen peptides of two different molecular weight ranges. Results show that higher molecular weight collagen peptides produce higher synthesis of collagen type I mRNA and, therefore, it may suggest that prior molecular weight selection may be an important step to maximize the effect of collagen hydrolysates on collagen type I synthesis by dermal fibroblasts.

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Effects of Dietary Supplementation with Fish Scales-Derived Collagen Peptides on Skin Parameters and Condition: A Randomized, Placebo-Controlled, Double-Blind Study

Cited by 23 publications

References 13 publications

Hydrolyzed Collagen—Sources and Applications

Hydrolyzed Collagen—Sources and Applications

Collagen supplementation for skin health: A mechanistic systematic review

Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture

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